|Application ||WB, E|
|Other Accession||NP_001124495.1, NP_000310.2, NP_001124496.1, NP_001124497.1|
|Calculated MW||70865 Da|
|Other Names||PEX5; peroxisomal biogenesis factor 5; FLJ50634; FLJ50721; FLJ51948; PTS1-BP; PTS1R; PXR1; OTTHUMP00000238192; OTTHUMP00000238193; OTTHUMP00000238194; OTTHUMP00000238195; OTTHUMP00000238353; OTTHUMP00000238354; OTTHUMP00000238356; PTS1 receptor; peroxin-5; peroxisomal C-terminal targeting signal import receptor; peroxisomal targeting signal 1 (SKL type) receptor; peroxisomal targeting signal 1 receptor; peroxisomal targeting signal import receptor; peroxisomal targeting signal receptor 1; peroxisome receptor 1|
|Format||Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.|
|Immunogen||Peptide with sequence C-QHTASDFVAKVDDPK, from the internal region of the protein sequence according to NP_001124495.1; NP_000310.2; NP_001124496.1; NP_001124497.1.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Goat Anti-PEX5 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import.|
|Cellular Location||Cytoplasm. Peroxisome membrane; Peripheral membrane protein. Note=Its distribution appears to be dynamic. It is probably a cycling receptor found mainly in the cytoplasm and as well associated to the peroxisomal membrane through a docking factor (PEX13)|
|Tissue Location||Detected in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Mapping the cargo protein membrane translocation step into the PEX5 cycling
pathway. Alencastre IS, Rodrigues TA, Grou CP, Fransen M, Sá-Miranda C, Azevedo JE. J Biol Chem. 2009 Oct 2;284(40):27243-51.
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