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>   home   >   Products   >   Primary Antibodies   >   Goat Anti-dUTPase / DUT Antibody (internal region)   

Goat Anti-dUTPase / DUT Antibody (internal region)

Purified Goat Polyclonal Antibody

  • WB - Goat Anti-dUTPase / DUT Antibody (internal region) AF4249a
    AF4249a (0.1 µg/ml) staining of HEK293 (A) and HeLa (B) lysates (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P33316
Other Accession NP_001020419.1, NP_001939.1, NP_001020420.1
Reactivity Human
Predicted Human, Pig, Cow
Host Goat
Clonality Polyclonal
Concentration 0.5
Calculated MW 26563 Da
Additional Information
Gene ID 1854
Other Names DUT; deoxyuridine triphosphatase; dUTPase; dUTP nucleotidohydrolase; dUTP pyrophosphatase; deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial
Format Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Immunogen Peptide with sequence C-QLRFARLSEHATAPT, from the internal region of the protein sequence according to NP_001020419.1; NP_001939.1; NP_001020420.1.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-dUTPase / DUT Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name DUT
Function This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
Cellular Location Isoform 2: Nucleus.
Tissue Location Found in a variety of tissues. Isoform 3 expression is constitutive, while isoform 2 expression correlates with the onset of DNA replication (at protein level). Isoform 2 degradation coincides with the cessation of nuclear DNA replication (at protein level).
Citations (0)

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Kinetic mechanism of human dUTPase, an essential nucleotide pyrophosphatase enzyme. Tóth J, Varga B, Kovács M, Málnási-Csizmadia A, Vértessy BG. The Journal of biological chemistry 2007 Nov 282 (46): 33572-82.

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$ 325.00
Cat# AF4249a
(40 western blots)
Availability: 7-10 days
Bulk Size
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