|Application ||WB, E|
|Other Accession||NP_005098.2, NP_001138936.1|
|Calculated MW||41085 Da|
|Other Names||EXOG; endo/exonuclease (5'-3'), endonuclease G-like; ENDOGL1; ENDOGL2; ENGL; ENGL-a; ENGL-b; ENGLA; ENGLB; endo G-like 1; endonuclease G-like 1; endonuclease G-like 2; nuclease EXOG, mitochondrial|
|Format||Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.|
|Immunogen||Peptide with sequence C-KAKEQSGTQIRKP, from the C Terminus of the protein sequence according to NP_005098.2; NP_001138936.1.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Goat Anti-EXOG Antibody (C Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||ENDOGL1, ENDOGL2, ENGL|
|Function||Endo/exonuclease with nicking activity towards supercoiled DNA, a preference for single-stranded DNA and 5'-3' exonuclease activity.|
|Cellular Location||Mitochondrion inner membrane|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Apoptosis induced by persistent single-strand breaks in mitochondrial genome: critical role of EXOG (5'-EXO/endonuclease) in their repair. Tann AW, Boldogh I, Meiss G, Qian W, Van Houten B, Mitra S, Szczesny B. The Journal of biological chemistry 2011 Sep 286 (37): 31975-83.
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