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Goat Anti-EXOG Antibody (C Terminus)
Purified Goat Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9Y2C4 |
| Other Accession | NP_005098.2, NP_001138936.1 |
| Reactivity | Human |
| Predicted | Human |
| Host | Goat |
| Clonality | Polyclonal |
| Concentration | 0.5 |
| Calculated MW | 41085 Da |
| Gene ID | 9941 |
|---|---|
| Other Names | EXOG; endo/exonuclease (5'-3'), endonuclease G-like; ENDOGL1; ENDOGL2; ENGL; ENGL-a; ENGL-b; ENGLA; ENGLB; endo G-like 1; endonuclease G-like 1; endonuclease G-like 2; nuclease EXOG, mitochondrial |
| Format | Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing. |
| Immunogen | Peptide with sequence C-KAKEQSGTQIRKP, from the C Terminus of the protein sequence according to NP_005098.2; NP_001138936.1. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Goat Anti-EXOG Antibody (C Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | EXOG |
|---|---|
| Synonyms | ENDOGL1, ENDOGL2, ENGL |
| Function | Endo/exonuclease with nicking activity towards supercoiled DNA, a preference for single-stranded DNA and 5'-3' exonuclease activity. |
| Cellular Location | Mitochondrion inner membrane |
| Tissue Location | Ubiquitous. |
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Provided below are standard protocols that you may find useful for product applications.
References
Apoptosis induced by persistent single-strand breaks in mitochondrial genome: critical role of EXOG (5'-EXO/endonuclease) in their repair. Tann AW, Boldogh I, Meiss G, Qian W, Van Houten B, Mitra S, Szczesny B. The Journal of biological chemistry 2011 Sep 286 (37): 31975-83.
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