|Predicted||Human, Pig, Dog|
|Calculated MW||43199 Da|
|Other Names||GRPR; gastrin-releasing peptide receptor; BB2; GRP-R; GRP-preferring bombesin receptor; bombesin receptor 2|
|Format||Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.|
|Immunogen||Peptide with sequence C-HPFHEESTNQT, from the internal region of the protein sequence according to NP_005305.1.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Goat Anti-GRPR Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Receptor for gastrin releasing peptide (GRP). This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
|Tissue Location||Highly expressed in pancreas. Also expressed in stomach, adrenal cortex and brain|
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Provided below are standard protocols that you may find useful for product applications.
The human gastrin-releasing peptide receptor gene structure, its tissue expression and promoter. Xiao D, Wang J, Hampton LL, Weber HC. Gene 2001 Feb 264 (1): 95-103.
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