|Application ||WB, E|
|Other Accession||15528(mouse), 25462(rat), NP_002148.1|
|Predicted||Human, Mouse, Rat, Pig, Cow, Dog|
|Calculated MW||10932 Da|
|Other Names||HSPE1; heat shock 10kDa protein 1; CPN10; EPF; GROES; HSP10; 10 kDa chaperonin; 10 kDa heat shock protein, mitochondrial; chaperonin 10; early-pregnancy factor; heat shock 10kD protein 1 (chaperonin 10)|
|Format||Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.|
|Immunogen||Peptide with sequence C-PEKSQGKVLQAT, from the internal region of the protein sequence according to NP_002148.1.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Goat Anti-CPN10 / HSPE1 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Eukaryotic CPN10 homolog which is essential for mitochondrial protein biogenesis, together with CPN60. Binds to CPN60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.|
|Cellular Location||Mitochondrion matrix.|
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Provided below are standard protocols that you may find useful for product applications.
Macromolecular crowding extended to a heptameric system: the Co-chaperonin protein 10. Aguilar X, F Weise C, Sparrman T, Wolf-Watz M, Wittung-Stafshede P. Biochemistry 2011 Apr 50 (14): 3034-44.
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