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Goat Anti-GSTM4 Antibody (internal region)
Purified Goat Polyclonal Antibody
- SPECIFICATION
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- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q03013 |
| Other Accession | NP_000841.1, NP_671489.1, 2948, 14865 (mouse), 499689 (rat) |
| Reactivity | Human |
| Predicted | Mouse |
| Host | Goat |
| Clonality | Polyclonal |
| Calculated MW | 25561 Da |
| Gene ID | 2948 |
|---|---|
| Other Names | GSTM4; glutathione S-transferase mu 4; GSTM4-4; GTM4; GST class-mu 4; GST-Mu2; GTS-Mu2; S-(hydroxyalkyl)glutathione lyase M4; glutathione S-alkyltransferase M4; glutathione S-aralkyltransferase M4; glutathione S-aryltransferase M4; glutathione S-transfera |
| Target/Specificity | This antibody is expected to recognize both reported isoforms (NP_000841.1; NP_671489.1). |
| Format | Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing. |
| Immunogen | Peptide with sequence DVSNQLARVCYSPD, from the internal region of the protein sequence according to NP_000841.1; NP_671489.1. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Goat Anti-GSTM4 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | GSTM4 |
|---|---|
| Function | Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles (PubMed:8203914, PubMed:8373352). Catalyzes the conjugation of leukotriene A4 with reduced glutathione (GSH) to form leukotriene C4 (PubMed:27791009). Can also catalyzes the transfer of a glutathionyl group from glutathione (GSH) to 13(S),14(S)-epoxy-docosahexaenoic acid to form maresin conjugate in tissue regeneration 1 (MCTR1), a bioactive lipid mediator that possess potent anti-inflammatory and proresolving actions (PubMed:27791009). |
| Cellular Location | Cytoplasm. |
| Tissue Location | Expressed in a wide variety of tissues. |
Research Areas
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
References
Luo W, Gangwal K, Sankar S, Boucher KM, Thomas D, Lessnick SL.
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$ 341.00
Cat# AF4312a
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