Register or Login
  • All
  • Uniprot Id
  • Catalog #
  • Peptide Sequence
>   home   >   Products   >   Primary Antibodies   >   KVbeta2 Antibody   

KVbeta2 Antibody

Affinity purified polyclonal antibody

  • WB - KVbeta2 Antibody AG1096-050
    Western blot analysis of rat brain lysate (lanes 1 and 3) and membranes (lanes 2 and 4):
    1, 2. Anti-Kvβ2 antibody (#AG1096), (1:200).
    3, 4.  Anti-Kvβ2 antibody, preincubated with the control peptide antigen.
  • WB - KVbeta2 Antibody AG1096-050
    Western blot analysis of human Jurkat T cells:
    1.  Anti-Kvβ2 antibody (#AG1096), (1:200).
    2.  Anti-Kvβ2 antibody, preincubated with the control peptide antigen.
  • IHC - KVbeta2 Antibody AG1096-050
    Expression of Kvβ2 in mouse cerebellum

    Immunohistochemical staining of mouse cerebellum using Anti-Kvβ2 antibody (#AG1096). A. Kvβ2 appears adjacent to Purkinje cells (green). B. Staining of GABAergic cells with mouse anti parvalbumin (PV, red). C. Confocal merge of Kvβ2 and PV demonstrates presence of Kvβ2 adjacent to Purkinje cells.

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P62483
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 41021 Da
Homology Mouse, human, rabbit - identical.
Additional Information
Gene ID 29738
Other Names Voltage-gated potassium channel subunit beta-2, K(+) channel subunit beta-2, Kv-beta-2, Kcnab2, Ckbeta2, Kcnb3
Related products for control experimentsControl peptide antigen (supplied with the antibody free of charge).
Target/Specificity Peptide SPGMIYSTRYGSPKR(C), corresponding to amino acid residues 20-34 of rat Kv־²2 (Accession P62483).ֲ ֲ N-terminal part.
Dilution WB~~1:200-1:2000
Peptide Confirmation Confirmed by mass-spectrography and amino acid analysis.
Format Affinity purified antibody, lyophilized powder
Reconstitution 50 µl or 0.2 ml deionized water, depending on the sample size.
Antibody Concentration After Reconstitution 0.8 mg/ml.
Buffer After Reconstitution Phosphate buffered saline (PBS), pH 7.4, 1% BSA, 0.025% NaN3.
Storage Before ReconstitutionLyophilized powder can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Storage After ReconstitutionThe reconstituted solution can be stored at 4ºC for up to 2 weeks. For longer periods, small aliquots should be stored at -20ºC or below. Avoid multiple freezing and thawing. The further dilutions should be made using a carrier protein such as BSA (1%). Centrifuge all antibody preparations before use (10000 × g 5 min).
Control Antigen Storage Before ReconstitutionLyophilized powder can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Control Antigen Reconstitution 100 µl water.
Control Antigen Storage After Reconstitution-20ºC.
Preadsorption Control 1 µg peptide per 1 µg antibody.
Citations (0)

Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.

Submit your citation using an Abgent antibody to, and receive a free "I Love Antibodies" mug.


Kvβ2 (or KCNAB2) is a member of a family of proteins that regulate the activity of voltage-dependent K+ channels. The other members of the family are Kvβ1 and Kvβ3. The Kvβ subunits were originally identified using a biochemical approach that demonstrated that the ion-conducting a subunits existed in a macromolecular complex with auxiliary β subunits with a probable stoichiometry of α4β4. It is now widely established that the regulatory β subunits are able to alter both the biophysical (i.e. acceleration of inactivation kinetics) and biochemical (promote cell surface expression) properties of the functional Kv channel. The Kvβ regulatory subunits are cytosolic proteins with conserved C-termini and variable N-terminus domains. The interaction with the a subunits is via the conserved C-terminal end that binds to a specific sequence in the N-terminus domain of the a subunits. Kvβ2, as well as the other Kvβ subunits can bind to all the members of the large Kv1.x (Shaker) channel subfamily.  However, recent evidence suggests that it can also bind to members of the Kv4.x subfamily. Kvβ2 is the most abundant β subunit in the brain where it couples with all the Kv1.x subunits, but the protein is also expressed in peripheral tissues including heart, lung and cells of hematopoietic origin such as T cells where it couples with Kv1.3, the dominant voltage-dependent K+ channel in these cells. We have now developed a highly specific antibody directed against a unique region in the N-terminus end of the rat Kvβ2 protein. The antibody will also recognize Kvβ2 samples from mouse and human origin.


References 1. Parcej, D.N. et al.  (1992) Biochemistry 31, 11084. 2. Rettig, J. et al. (1994) Nature 369, 289. 3. Pongs, O. et al. (1999) Ann. N. Y. Acad. Sci. 868, 344. 4. Li, Y. et al. (2006) Neuroscientist 12, 199.

Abgent welcomes feedback from its customers.

If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.

If you have any additional inquiries please email technical services at

$ 367.00
$ 475.00
Cat# AG1096-050
Availability: 2-3 weeks
Bulk Size
Seasonal Special on Bulk Order
Request Quote Here

Ordering Information

United States
AlbaniaAustraliaAustriaBelgiumBosnia & HerzegovinaBrazilBulgariaCanadaCentral AmericaChinaCroatiaCyprusCzech RepublicDenmarkEstoniaFinlandFranceGermanyGreeceHong KongHungaryIcelandIndiaIndonesiaIrelandIsraelItalyJapanLatviaLithuaniaLuxembourgMacedoniaMalaysiaMaltaNetherlandsNew ZealandNorwayPakistanPolandPortugalRomaniaSerbiaSingaporeSlovakiaSloveniaSouth AfricaSouth KoreaSpainSwedenSwitzerlandTaiwanTurkeyUnited KingdomUnited StatesVietnamWorldwideOthers
Abgent, Inc.
(888) 735-7227 / (858) 622-0099
(858) 622-0609
USA Headquarters
(888) 735-7227 / (858) 622-0099 or (858) 875-1900

Other Products

Shipping Information

Domestic orders (in stock items)
Shipped out the same day. Orders placed after 1 PM (PST) will ship out the next business day.
International orders
Contact your local distributors
Crown Flash21-30% Off
Terms & Conditions