Register or Login
  • All
  • Uniprot Id
  • Catalog #
  • Peptide Sequence
>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   KCa1.1 (1184-1200) Antibody   

KCa1.1 (1184-1200) Antibody

Affinity purified polyclonal antibody

  • WB - KCa1.1 (1184-1200) Antibody AG1403-025
    Western blot analysis of rat brain membranes: 
    1. Anti-KCa1.1 (1184-1200) antibody (#AG1403), (1:500). 
    2. Anti-KCa1.1 (1184-1200) antibody, preincubated with the control peptide antigen.
  • WB - KCa1.1 (1184-1200) Antibody AG1403-025
    Immunoprecipitation of rat brain lysate: 1. Brain lysate
    2. Brain lysate immunoprecipitated with Anti-KCa1.1 (1184-1200) antibody (#AG1403), (4 μg).
    3. Brain lysate immunoprecipitated with pre-immune rabbit
    The upper arrow indicates the KCa1.1 channel while the lower arrow indicates the IgG heavy chain.
    Western blot analysis was performed with Anti-KCa1.1 (1184-1200) antibody.
  • IHC - KCa1.1 (1184-1200) Antibody AG1403-025
    Expression of KCa1.1 in rat penis.
    Immunohistochemical staining of rat penis transversal section using Anti-KCa1.1 (1184-1200) antibody (#AG1403).  Strong and specific immunostaining is evident in both corpus cavernosum smooth muscle cells (blue arrow) and in the muscular layer of the penis artery (green arrow).  Universal Immuno-alkaline-phosphatase Polymer followed by New Fuchsin Subtrate (histofine, Nichirei Corp.) was used for the color reaction.  Hematoxillin is used as the counterstain.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q08460
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 134396 Da
Homology Rat- identical; human, bovine, chicken, dog - 16/17 amino acid residues identical.
Additional Information
Gene ID 16531
Other Names Calcium-activated potassium channel subunit alpha-1, BK channel, BKCA alpha, Calcium-activated potassium channel, subfamily M subunit alpha-1, K(VCA)alpha, KCa11, Maxi K channel, MaxiK, Slo-alpha, Slo1, mSlo1, Slowpoke homolog, Slo homolog, mSlo, Kcnma1, Kcnma
Related products for control experimentsControl peptide antigen (supplied with the antibody free of charge).
Target/Specificity Peptide (C)STANRPNRPKSRESRDK, corresponding to amino acid residues 1184-1200 of mouse KCa1.1ֲ (Accession number Q08460). Intracellular, C-terminal part.
Dilution WB~~1:200-1:2000
Peptide Confirmation Confirmed by mass-spectrography and amino acid analysis.
Application Details Western blot analysis (WB): - Mouse kidney lysates (see Zhang, Y. et al. (2013) in Product Citations). - Mitochondria and mitoplast from human endothelial EA.hy926 cells (1:200) (see Bednarczyk, P. et al. (2013) in Product Citations).   Immunoprecipitation (IP): - Human cardiac fibroblasts (1:750) (see Wang, Y.J. et al. (2006) in Product Citations). Immunocytochemistry (IC): - Human chorionic plate arterial smooth muscle cells (10 µg/ml) (see Brereton, M.F. et al. (2013) in Product Citations). - Mouse mesenteric smooth muscle cells (1:100) (see Suzuki, Y. et al. (2013) in Product Citations). - E9 chick CG neurons (see Jha, S. and Dryer, S.T. (2009) in Product Citations). Immunohistochemistry (IH): - Human chorionic plate arterial smooth muscle cell sections (10 µg/ml) (see Brereton, M.F. et al. (2013) in Product Citations).  
Format Affinity purified antibody, lyophilized powder
Reconstitution 25 µl, 50 µl or 0.2 ml deionized water, depending on the sample size.
Antibody Concentration After Reconstitution 0.4 mg/ml.
Storage Before ReconstitutionLyophilized powder can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Storage After ReconstitutionThe reconstituted solution can be stored at 4ºC for up to 2 weeks. For longer periods, small aliquots should be stored at -20ºC or below. Avoid multiple freezing and thawing. The further dilutions should be made using a carrier protein such as BSA (1%). Centrifuge all antibody preparations before use (10000 × g 5 min).
Control Antigen Storage Before ReconstitutionLyophilized powder can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Control Antigen Reconstitution 100 µl water.
Control Antigen Storage After Reconstitution-20ºC.
Preadsorption Control 1 µg peptide per 1 µg antibody.
Formulation Lyophilized powder. Reconstituted antibody contains phosphate buffered saline (PBS), pH 7.4, 1% BSA, 0.05% NaN3.
Research Areas
Citations (0)

Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.

Submit your citation using an Abgent antibody to, and receive a free "I Love Antibodies" mug.


KCa1.1 (BKCa, Maxi K+ or slo) is part of a structurally diverse group of K+ channels that are activated by an increase in intracellular Ca2+. KCa1.1 shows a large single channel conductance when recorded electrophysiologically and hence its name. It differs from the rest of the subfamily members in that it can be activated by both an increase in intracellular Ca2+ and by membrane depolarization.   KCa1.1 is expressed in virtually all cell types where it causes hyperpolarization and helps to connect between intracellular Ca2+ signaling pathways and membrane excitability.   Indeed, KCa1.1 channels have a crucial role in smooth muscle contractility, neuronal spike shaping and neurotransmitter release.


References 1. Hofland L.J. and Lamberts, S.W.J. (2001) Annals of Oncology 12, S31. 2. Fombonne, J. et al. (2003) Rep. Biol. Endocrinol. 1, 19. 3. Slooter, G.D. et al. (2001) Br. J. Surg. 88, 31. 4. Schulz, S. et al. (2002) Gynecologic Oncology 84, 235.

Abgent welcomes feedback from its customers.

If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.

If you have any additional inquiries please email technical services at

$ 247.00
$ 367.00
$ 475.00
Cat# AG1403-025
Availability: 2-3 weeks
Bulk Size
Seasonal Special on Bulk Order
Request Quote Here

Ordering Information

United States
AlbaniaAustraliaAustriaBelgiumBosnia & HerzegovinaBrazilBulgariaCanadaCentral AmericaChinaCroatiaCyprusCzech RepublicDenmarkEstoniaFinlandFranceGermanyGreeceHong KongHungaryIcelandIndiaIndonesiaIrelandIsraelItalyJapanLatviaLithuaniaLuxembourgMacedoniaMalaysiaMaltaNetherlandsNew ZealandNorwayPakistanPolandPortugalRomaniaSerbiaSingaporeSlovakiaSloveniaSouth AfricaSouth KoreaSpainSwedenSwitzerlandTaiwanTurkeyUnited KingdomUnited StatesVietnamWorldwideOthers
Abgent, Inc.
(888) 735-7227 / (858) 622-0099
(858) 622-0609
USA Headquarters
(888) 735-7227 / (858) 622-0099 or (858) 875-1900

Shipping Information

Domestic orders (in stock items)
Shipped out the same day. Orders placed after 1 PM (PST) will ship out the next business day.
International orders
Contact your local distributors
“Crown Flash”  50 % off on 1,800+ Crown Antibodies. PromoCode:<span class=text-red> FLASH50
Terms & Conditions