|Calculated MW||43269 Da|
|Homology||Rat, mouse, human - 15/16 amino acid residues identical.|
|Other Names||Voltage-dependent calcium channel gamma-8 subunit, Neuronal voltage-gated calcium channel gamma-8 subunit, Transmembrane AMPAR regulatory protein gamma-8, TARP gamma-8, Cacng8|
|Related products for control experiments||Control peptide antigen (supplied with the antibody free of charge).|
|Format||Lyophilized powder. Reconstituted antibody contains phosphate buffered saline (PBS), pH 7.4, 1% BSA, 0.05% NaN3.|
|Storage Before Reconstitution||Lyophilized powder can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.|
|Storage After Reconstitution||The reconstituted solution can be stored at 4ºC for up to 2 weeks. For longer periods, small aliquots should be stored at -20ºC or below. Avoid multiple freezing and thawing. The further dilutions should be made using a carrier protein such as BSA (1%). Centrifuge all antibody preparations before use (10000 × g 5 min).|
|Control Antigen Storage Before Reconstitution||Lyophilized powder can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.|
|Control Antigen Storage After Reconstitution||-20ºC.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state.
Chu P.-J.,et al.Gene 280:37-48(2001).
Milstein A.D.,et al.Neuron 55:905-918(2007).
Soto D.,et al.Nat. Neurosci. 12:277-285(2009).
Soto D.,et al.Nat. Neurosci. 12:808-808(2009).
Schwenk J.,et al.Science 323:1313-1319(2009).
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