|Application ||WB, IHC|
|Reactivity||Human, Mouse, Rat|
|Calculated MW||104071 Da|
|Homology||Human, mouse - identical.|
|Other Names||Glutamate receptor ionotropic, kainate 3, GluK3, Glutamate receptor 7, GluR-7, GluR7, Grik3, Glur7|
|Related products for control experiments||Control peptide antigen (supplied with the antibody free of charge).|
|Format||Lyophilized powder. Reconstituted antibody contains phosphate buffered saline (PBS), pH 7.4, 1% BSA, 0.05% NaN3.|
|Storage Before Reconstitution||Lyophilized powder can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.|
|Storage After Reconstitution||The reconstituted solution can be stored at 4ºC for up to 2 weeks. For longer periods, small aliquots should be stored at -20ºC or below. Avoid multiple freezing and thawing. The further dilutions should be made using a carrier protein such as BSA (1%). Centrifuge all antibody preparations before use (10000 × g 5 min).|
|Control Antigen Storage Before Reconstitution||Lyophilized powder can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.|
|Control Antigen Storage After Reconstitution||-20ºC.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists. This receptor binds domoate > kainate >> L-glutamate = quisqualate >> AMPA = NMDA.
Lomeli H.,et al.FEBS Lett. 307:139-143(1992).
Sprengel R.,et al.Submitted (APR-1994) to the EMBL/GenBank/DDBJ databases.
Schiffer H.H.,et al.Neuron 19:1141-1146(1997).
Bettler B.,et al.Neuron 8:257-265(1992).
El Far O.,et al.Eur. J. Neurosci. 12:4215-4221(2000).
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