|Application ||WB, IHC|
|Reactivity||Human, Mouse, Rat|
|Calculated MW||109276 Da|
|Homology||Human, mouse - identical.|
|Other Names||Glutamate receptor ionotropic, kainate 5, GluK5, Glutamate receptor KA-2, KA2, Grik5|
|Related products for control experiments||Control peptide antigen (supplied with the antibody free of charge).|
|Format||Lyophilized powder. Reconstituted antibody contains phosphate buffered saline (PBS), pH 7.4, 1% BSA, 0.05% NaN3.|
|Storage Before Reconstitution||Lyophilized powder can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.|
|Storage After Reconstitution||The reconstituted solution can be stored at 4ºC for up to 2 weeks. For longer periods, small aliquots should be stored at -20ºC or below. Avoid multiple freezing and thawing. The further dilutions should be made using a carrier protein such as BSA (1%). Centrifuge all antibody preparations before use (10000 × g 5 min).|
|Control Antigen Storage Before Reconstitution||Lyophilized powder can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.|
|Control Antigen Storage After Reconstitution||-20ºC.|
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Provided below are standard protocols that you may find useful for product applications.
Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists. This receptor binds kainate > quisqualate > glutamate >> AMPA.
Herb A.,et al.Neuron 8:775-785(1992).
Boulter J.,et al.Submitted (MAY-1994) to the EMBL/GenBank/DDBJ databases.
Kumar J.,et al.J. Mol. Biol. 404:680-696(2010).
Kumar J.,et al.Neuron 71:319-331(2011).
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