|Reactivity||Human, Mouse, Rat|
|Calculated MW||55927 Da|
|Homology||Mouse, human - identical.|
|Other Names||Glycine receptor subunit beta, Glycine receptor 58 kDa subunit, Glrb|
|Related products for control experiments||Control peptide antigen (supplied with the antibody free of charge).|
|Format||Lyophilized powder. Reconstituted antibody contains phosphate buffered saline (PBS), pH 7.4, 1% BSA, 0.05% NaN3.|
|Storage Before Reconstitution||Lyophilized powder can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.|
|Storage After Reconstitution||The reconstituted solution can be stored at 4ºC for up to 2 weeks. For longer periods, small aliquots should be stored at -20ºC or below. Avoid multiple freezing and thawing. The further dilutions should be made using a carrier protein such as BSA (1%). Centrifuge all antibody preparations before use (10000 × g 5 min).|
|Control Antigen Storage Before Reconstitution||Lyophilized powder can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.|
|Control Antigen Storage After Reconstitution||-20ºC.|
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Provided below are standard protocols that you may find useful for product applications.
The glycine receptor is a neurotransmitter-gated ion channel. Binding of glycine to its receptor increases the chloride conductance and thus produces hyperpolarization (inhibition of neuronal firing).
Grenningloh G.,et al.Neuron 4:963-970(1990).
Burzomato V.,et al.J. Neurosci. 24:10924-10940(2004).
Sola M.,et al.EMBO J. 23:2510-2519(2004).
Kim E.Y.,et al.EMBO J. 25:1385-1395(2006).
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