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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Sigma-1 Receptor Antibody   

Sigma-1 Receptor Antibody

Purified Rabbit Polyclonal Antibody

  • WB - Sigma-1 Receptor Antibody AG1512-025
    Western blot analysis of rat liver (lanes 1 and 3) and mouse liver (lanes 2 and 4) membranes:1, 2. Anti-Sigma-1 Receptor antibody (AG1512), (1:200)3, 4. Anti-Sigma-1 Receptor antibody preincubated with the control peptide antigen.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q99720
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Calculated MW 25128 Da
Homology Rat, Mouse - identical. 
Additional Information
Gene ID 10280
Other Names Sigma non-opioid intracellular receptor 1, Aging-associated gene 8 protein, SR31747-binding protein, SR-BP, Sigma 1-type opioid receptor, SIG-1R, Sigma1-receptor, Sigma1R, hSigmaR1, SIGMAR1, OPRS1, SRBP
Related products for control experimentsControl peptide antigen (supplied with the antibody free of charge).
Format Lyophilized powder. Reconstituted antibody contains phosphate buffered saline (PBS), pH 7.4, 1% BSA, 0.05% NaN3.
Storage Before ReconstitutionLyophilized powder can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Storage After ReconstitutionThe reconstituted solution can be stored at 4ºC for up to 2 weeks. For longer periods, small aliquots should be stored at -20ºC or below. Avoid multiple freezing and thawing. The further dilutions should be made using a carrier protein such as BSA (1%). Centrifuge all antibody preparations before use (10000 × g 5 min).
Control Antigen Storage Before ReconstitutionLyophilized powder can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Control Antigen Storage After Reconstitution-20ºC.
Research Areas
Citations (0)

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Functions in lipid transport from the endoplasmic reticulum and is involved in a wide array of cellular functions probably through regulation of the biogenesis of lipid microdomains at the plasma membrane. Involved in the regulation of different receptors it plays a role in BDNF signaling and EGF signaling. Also regulates ion channels like the potassium channel and could modulate neurotransmitter release. Plays a role in calcium signaling through modulation together with ANK2 of the ITP3R-dependent calcium efflux at the endoplasmic reticulum. Plays a role in several other cell functions including proliferation, survival and death. Originally identified for its ability to bind various psychoactive drugs it is involved in learning processes, memory and mood alteration.


Kekuda R.,et al.Biochem. Biophys. Res. Commun. 229:553-558(1996).
Jbilo O.,et al.J. Biol. Chem. 272:27107-27115(1997).
Prasad P.D.,et al.J. Neurochem. 70:443-451(1998).
Wang L.-M.,et al.Submitted (JAN-2000) to the EMBL/GenBank/DDBJ databases.
Kim J.W.,et al.Submitted (MAY-2004) to the EMBL/GenBank/DDBJ databases.

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$ 375.00
$ 475.00
$ 575.00
Cat# AG1512-025
(40 western blots)
Availability: 2-3 weeks
Bulk Size
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