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>   home   >   Products   >   Primary Antibodies   >   Stem Cells   >   N-Cadherin Antibody   

N-Cadherin Antibody

Purified Rabbit Polyclonal Antibody

  • WB - N-Cadherin Antibody AG1542-025
    Western blot analysis of mouse brain (lanes 1 and 5), mouse heart (lanes 2 and 6), rat heart (lanes 3 and 7) and human brain neuroblastoma (SH-SY5Y) (lanes 4 and 8) cell lysates:1-4.Anti-N-Cadherinantibody (#AG1542), (1:200).5-8. Anti-N-Cadherin antibody preincubated with the control peptide antigen.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P15116
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Calculated MW 99796 Da
Homology Rat, human - identical.
Additional Information
Gene ID 12558
Other Names Cadherin-2, Neural cadherin, N-cadherin, CD325, Cdh2
Related products for control experimentsControl peptide antigen (supplied with the antibody free of charge).
Format Lyophilized powder. Reconstituted antibody contains phosphate buffered saline (PBS), pH 7.4, 1% BSA, 0.05% NaN3.
Storage Before ReconstitutionLyophilized powder can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Storage After ReconstitutionThe reconstituted solution can be stored at 4ºC for up to 2 weeks. For longer periods, small aliquots should be stored at -20ºC or below. Avoid multiple freezing and thawing. The further dilutions should be made using a carrier protein such as BSA (1%). Centrifuge all antibody preparations before use (10000 × g 5 min).
Control Antigen Storage Before ReconstitutionLyophilized powder can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Control Antigen Storage After Reconstitution-20ºC.
Research Areas
Citations (0)

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Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence (PubMed:24952463). CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density.


Miyatani S.,et al.Science 245:631-635(1989).
Tamura K.,et al.Submitted (NOV-1997) to the EMBL/GenBank/DDBJ databases.
Miyatani S.,et al.Proc. Natl. Acad. Sci. U.S.A. 89:8443-8447(1992).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Munro S.B.,et al.Biol. Reprod. 55:822-827(1996).

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$ 375.00
$ 475.00
$ 575.00
Cat# AG1542-025
(40 western blots)
Availability: 2-3 weeks
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