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Piezo1 Antibody

Purified Rabbit Polyclonal Antibody

  • WB - Piezo1 Antibody AG1563-025
    Western blot analysis of rat lung (lanes 1 and 3) and mouse lung (lanes 2 and 4) lysates:1,2.Anti-Piezo1 antibody (#AG1563), (1:600).3,4. Anti-Piezo1 antibody preincubated with the control peptide antigen.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q0KL00
Reactivity Mouse
Host Rabbit
Clonality Polyclonal
Calculated MW 290315 Da
Homology Mouse - 12/14 amino acid residues identical.
Additional Information
Gene ID 361430
Other Names Piezo-type mechanosensitive ion channel component 1, Membrane protein induced by beta-amyloid treatment, Mib, Protein FAM38A, Piezo1, Fam38a
Related products for control experimentsControl peptide antigen (supplied with the antibody free of charge).
Format Lyophilized powder. Reconstituted antibody contains phosphate buffered saline (PBS), pH 7.4, 1% BSA, 0.05% NaN3.
Storage Before ReconstitutionLyophilized powder can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Storage After ReconstitutionThe reconstituted solution can be stored at 4ºC for up to 2 weeks. For longer periods, small aliquots should be stored at -20ºC or below. Avoid multiple freezing and thawing. The further dilutions should be made using a carrier protein such as BSA (1%). Centrifuge all antibody preparations before use (10000 × g 5 min).
Control Antigen Storage Before ReconstitutionLyophilized powder can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Control Antigen Storage After Reconstitution-20ºC.
Citations (0)

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Pore-forming subunit of a mechanosensitive non-specific cation channel. Plays a key role in epithelial cell adhesion by maintaining integrin activation through R-Ras recruitment to the ER, most probably in its activated state, and subsequent stimulation of calpain signaling. In the kidney, may contribute to the detection of intraluminal pressure changes and to urine flow sensing. Acts as shear-stress sensors that promote endothelial cell organization and alignment in the direction of blood flow. Plays a key role in blood vessel formation and vascular structure in both development and adult physiology.


Gibbs R.A.,et al.Nature 428:493-521(2004).
Satoh K.,et al.Brain Res. 1108:19-27(2006).

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$ 375.00
$ 475.00
$ 575.00
Cat# AG1563-025
(40 western blots)
Availability: 2-3 weeks
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