|Application ||WB, IHC|
|Reactivity||Human, Mouse, Rat|
|Calculated MW||211067 Da|
|Homology||Mouse, rat - 13/14 amino acid residues identical.|
|Other Names||Plexin-A1, Semaphorin receptor NOV, PLXNA1, NOV, PLXN1|
|Related products for control experiments||Control peptide antigen (supplied with the antibody free of charge).|
|Format||Lyophilized powder. Reconstituted antibody contains phosphate buffered saline (PBS), pH 7.4, 1% BSA, 0.05% NaN3.|
|Storage Before Reconstitution||Lyophilized powder can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.|
|Storage After Reconstitution||The reconstituted solution can be stored at 4ºC for up to 2 weeks. For longer periods, small aliquots should be stored at -20ºC or below. Avoid multiple freezing and thawing. The further dilutions should be made using a carrier protein such as BSA (1%). Centrifuge all antibody preparations before use (10000 × g 5 min).|
|Control Antigen Storage Before Reconstitution||Lyophilized powder can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.|
|Control Antigen Storage After Reconstitution||-20ºC.|
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Coreceptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down- stream signaling events in the cytoplasm (By similarity).
Muzny D.M.,et al.Nature 440:1194-1198(2006).
Maestrini E.,et al.Proc. Natl. Acad. Sci. U.S.A. 93:674-678(1996).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Wollscheid B.,et al.Nat. Biotechnol. 27:378-386(2009).
Burkard T.R.,et al.BMC Syst. Biol. 5:17-17(2011).
If you have any additional inquiries please email technical services at email@example.com.