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Shank1 Antibody

Purified Rabbit Polyclonal Antibody

  • WB - Shank1 Antibody AG1587-025
    Western blot analysis of mouse brain lysate (lanes 1 and 3) and rat brain lysate (lanes 2 and 4):1,2.Anti-Shank1antibody (#AG1587), (1:400).3,4. Anti- Shank1 antibody, preincubated with the control peptide antigen.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9WV48
Reactivity Mouse
Host Rabbit
Clonality Polyclonal
Calculated MW 226335 Da
Homology Mouse - identical; human - 13/15 amino acid residues identical.
Additional Information
Gene ID 78957
Other Names SH3 and multiple ankyrin repeat domains protein 1, Shank1, GKAP/SAPAP-interacting protein, SPANK-1, Somatostatin receptor-interacting protein, SSTR-interacting protein, SSTRIP, Synamon, Shank1
Related products for control experimentsControl peptide antigen (supplied with the antibody free of charge).
Format Lyophilized powder. Reconstituted antibody contains phosphate buffered saline (PBS), pH 7.4, 1% BSA, 0.05% NaN3.
Storage Before ReconstitutionLyophilized powder can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Storage After ReconstitutionThe reconstituted solution can be stored at 4ºC for up to 2 weeks. For longer periods, small aliquots should be stored at -20ºC or below. Avoid multiple freezing and thawing. The further dilutions should be made using a carrier protein such as BSA (1%). Centrifuge all antibody preparations before use (10000 × g 5 min).
Control Antigen Storage Before ReconstitutionLyophilized powder can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Control Antigen Storage After Reconstitution-20ºC.
Research Areas
Citations (0)

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Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors, and the actin-based cytoskeleton. Plays a role in the structural and functional organization of the dendritic spine and synaptic junction. Overexpression promotes maturation of dendritic spines and the enlargement of spine heads via its ability to recruit Homer to postsynaptic sites, and enhances presynaptic function.


Yao I.,et al.J. Biol. Chem. 274:27463-27466(1999).
Naisbitt S.,et al.Neuron 23:569-582(1999).
Tobaben S.,et al.J. Biol. Chem. 275:36204-36210(2000).
Lim S.,et al.J. Biol. Chem. 274:29510-29518(1999).
Zitzer H.,et al.J. Biol. Chem. 274:32997-33001(1999).

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$ 375.00
$ 475.00
$ 575.00
Cat# AG1587-025
(40 western blots)
Availability: 2-3 weeks
Bulk Size
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