|Application ||WB, ICC|
|Calculated MW||46107 Da|
|Homology||Mouse - 12/13 amino acid residues identical; human - 11/13 amino acid residues identical.|
|Other Names||5-hydroxytryptamine receptor 4, 5-HT-4, 5-HT4, Serotonin receptor 4, Htr4|
|Related products for control experiments||Control peptide antigen (supplied with the antibody free of charge).|
|Format||Lyophilized powder. Reconstituted antibody contains phosphate buffered saline (PBS), pH 7.4, 1% BSA, 0.05% NaN3.|
|Storage Before Reconstitution||Lyophilized powder can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.|
|Storage After Reconstitution||The reconstituted solution can be stored at 4ºC for up to 2 weeks. For longer periods, small aliquots should be stored at -20ºC or below. Avoid multiple freezing and thawing. The further dilutions should be made using a carrier protein such as BSA (1%). Centrifuge all antibody preparations before use (10000 × g 5 min).|
|Control Antigen Storage Before Reconstitution||Lyophilized powder can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.|
|Control Antigen Storage After Reconstitution||-20ºC.|
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Provided below are standard protocols that you may find useful for product applications.
This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase.
Gerald C.,et al.EMBO J. 14:2806-2815(1995).
Ullmer C.,et al.FEBS Lett. 370:215-221(1995).
Claeysen S.,et al.Mol. Pharmacol. 55:910-920(1999).
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