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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >    CD147 / EMMPRIN / Neurothelin Antibody - With BSA and Azide   

CD147 / EMMPRIN / Neurothelin Antibody - With BSA and Azide

Purified Mouse Monoclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P35613
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names 8D6
Calculated MW 35kDa (non-reduced); 40kDa (reduced)
Additional Information
Gene ID 682
Other Names Basigin, 5F7, Collagenase stimulatory factor, Extracellular matrix metalloproteinase inducer, EMMPRIN, Leukocyte activation antigen M6, OK blood group antigen, Tumor cell-derived collagenase stimulatory factor, TCSF, CD147, BSG
Target/Specificity Human T cell line Molt 13
Application Note Inhibits Homotypic Aggregation, Adhesion to Matrix Proteins, and Migation through Matrigel : Order Ab without BSA/Azide
Flow Cytometry : 0.5-1ug/million cells
Immunofluorescence : 1:100-1:200
Immunoprecipitation : 1-2ug/500ug protein
Western Blotting : 0.5-1.0 µg/ml
Immunohistology (Frozen & Formalin-fixed) : 1-2ug/ml for 30 minutes at RT
(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes).
Format 0.5 ml at 200ug/ml with BSA and azide
StorageStore at 2 to 8°C.Antibody is stable for 24 months.
Precautions CD147 / EMMPRIN / Neurothelin Antibody - With BSA and Azide is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name BSG
Function Plays an important role in targeting the monocarboxylate transporters SLC16A1, SLC16A3 and SLC16A8 to the plasma membrane. Plays pivotal roles in spermatogenesis, embryo implantation, neural network formation and tumor progression. Stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS). Seems to be a receptor for oligomannosidic glycans. In vitro, promotes outgrowth of astrocytic processes.
Cellular Location Cell membrane; Single-pass type I membrane protein Melanosome. Note=Colocalizes with SLC16A1 and SLC16A8. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. {ECO:0000250|UniProtKB:P18572, ECO:0000269|PubMed:17081065}
Tissue Location Present only in vascular endothelium in non- neoplastic regions of the brain, whereas it is present in tumor cells but not in proliferating blood vessels in malignant gliomas
Research Areas
Citations (0)

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This MAb recognizes extracellular epitope 2 within the N-terminal Ig domain of human CD147. It expressed more intensely on thymocytes than on mature peripheral blood T cells. CD147 is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. It stimulates the production of interstitial collagenase, gelatinase A, stromelysin-1 and various metalloproteinases (MMPs) by fibroblasts. These enzymes are important factors in cancer invasion and metastasis.


1. Kirsch AH et. al. Tissue Antigens. 1997 Aug;50(2):147-52.

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$ 124.00
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$ 454.00
Cat# AH10051
(40 western blots)
Availability: 2-3 days
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