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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >    CD2 / Lymphocyte Function Antigen 2 (LFA-2) Antibody - With BSA and Azide   

CD2 / Lymphocyte Function Antigen 2 (LFA-2) Antibody - With BSA and Azide

Purified Mouse Monoclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P06729
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG2b, kappa
Clone Names BH1
Calculated MW 50kDa
Additional Information
Gene ID 914
Other Names T-cell surface antigen CD2, Erythrocyte receptor, LFA-2, LFA-3 receptor, Rosette receptor, T-cell surface antigen T11/Leu-5, CD2, CD2, SRBC
Target/Specificity Human CD2 protein
Application Note ELISA : For coating, order Ab without BSA
Functional Studies : Order Ab without Azide
Flow Cytometry : 0.5-1ug/million cells
Immunofluorescence : 0.5-1.0 µg/ml
Immunoprecipitation : 0.5-1 µg/500ug protein lysate
Immunohistology (Frozen) : 0.5-1.0 µg/ml for 30 minutes at RT.
Format 0.5 ml at 200ug/ml with BSA and azide
StorageStore at 2 to 8°C.Antibody is stable for 24 months.
Precautions CD2 / Lymphocyte Function Antigen 2 (LFA-2) Antibody - With BSA and Azide is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CD2
Synonyms SRBC
Function CD2 interacts with lymphocyte function-associated antigen (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T- cells, the cytoplasmic domain is implicated in the signaling function.
Cellular Location Membrane; Single-pass type I membrane protein
Research Areas
Citations (0)

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CD2 interacts through its amino-terminal domain with the extracellular domain of CD58 (also designated CD2 ligand) to mediate cell adhesion. CD2/CD58 binding can enhance antigen-specific T cell activation. CD2 is a transmembrane glycoprotein that is expressed on peripheral blood T lymphocytes, NK cells and thymocytes. CD58 is a heavily glycosylated protein with a broad tissue distribution in hematopoietic and other cells, including endothelium. Interaction between CD2 and its counter receptor LFA3 (CD58) on opposing cells optimizes immune system recognition, thereby facilitating communication between helper T lymphocytes and antigen-presenting cells, as well as between cytolytic effectors and target cells.


1. Wang MY et. al. An effective immuno-magnetic method for bone marrow purging in T cell malignancies. Bone Marrow Transplant. 1992;9(5):319-23.

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$ 124.00
$ 324.00
$ 454.00
Cat# AH10079
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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