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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >    CD30 / TNFRSF8 (Hodgkin & Reed-Sternberg Cell Marker) Antibody - With BSA and Azide   

CD30 / TNFRSF8 (Hodgkin & Reed-Sternberg Cell Marker) Antibody - With BSA and Azide

Purified Mouse Monoclonal Antibody

  •  -  CD30 / TNFRSF8 (Hodgkin & Reed-Sternberg Cell Marker) Antibody - With BSA and Azide AH10134
    Formalin-fixed, paraffin-embedded Hodgkin's lymphoma (20X) stained with CD30 Ab (CD30/412).
  •  -  CD30 / TNFRSF8 (Hodgkin & Reed-Sternberg Cell Marker) Antibody - With BSA and Azide AH10134
    Formalin-fixed, paraffin-embedded Hodgkin's lymphoma (20X) stained with CD30 Ab (CD30/412).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P28908
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG2b, kappa
Clone Names CD30/412
Calculated MW 105-120kDa
Additional Information
Gene ID 943
Other Names Tumor necrosis factor receptor superfamily member 8, CD30L receptor, Ki-1 antigen, Lymphocyte activation antigen CD30, CD30, TNFRSF8, CD30, D1S166E
Target/Specificity Human CD30 recombinant protein
Application Note ELISA : For coating, order Ab without BSA
Flow Cytometry : 0.5-1ug/million cells
Immunofluorescence : 1-2ug/ml
Immunohistology (Frozen & Formalin-fixed) : 0.5-1.0 µg/ml for 30 minutes at RT
(Staining of formalin-fixed tissues requires boiling tissue sections in 1mM EDTA, pH 7.5-8.5, for 10-20 min followed by cooling at RT for 20 minutes)
Format 0.5 ml at 200ug/ml with BSA and azide
StorageStore at 2 to 8°C.Antibody is stable for 24 months.
Precautions CD30 / TNFRSF8 (Hodgkin & Reed-Sternberg Cell Marker) Antibody - With BSA and Azide is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms CD30, D1S166E
Function Receptor for TNFSF8/CD30L. May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF- kappa-B.
Cellular Location Isoform 1: Cell membrane; Single-pass type I membrane protein
Research Areas
Citations (0)

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Recognizes a single chain glycoprotein of 105/120kDa, identified as CD30/Ki-1. CD30 is synthesized as a 90kDa precursor, which is processed in the Golgi complex into a membrane-bound phosphorylated mature 105/120kDa glycoprotein. In Hodgkin’s disease, CD30/Ki-1 antigen is expressed by mononuclear-Hodgkin and multinucleated Reed-Sternberg cells. It is also expressed by the tumor cells of a majority of anaplastic large cell lymphomas as well as by a varying proportion of activated T and B cells. This MAb distinguishes large cell lymphomas derived from activated lymphoid cells from histiocytic malignancies and lymphomas derived from resting and precursor lymphoid cells or from anaplastic carcinomas. About one third of the Ki-1 positive lymphomas lack the leukocyte common antigen (CD45).


1. Schwarting R, et. al. Blood, 1989, 74(5):1678-89.

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$ 124.00
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$ 454.00
Cat# AH10134
(40 western blots)
Availability: 2-3 days
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