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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >    CD35 / CR1 (Follicular Dendritic Cell Marker) Antibody - With BSA and Azide   

CD35 / CR1 (Follicular Dendritic Cell Marker) Antibody - With BSA and Azide

Purified Mouse Monoclonal Antibody

  •  -  CD35 / CR1 (Follicular Dendritic Cell Marker) Antibody - With BSA and Azide AH10160
    Formalin-fixed, paraffin-embedded human tonsil stained with CD35 Ab (E11). Note cell membrane staining.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P17927
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG1, kappa
Clone Names E11
Calculated MW 210-220kDa
Additional Information
Gene ID 1378
Other Names Complement receptor type 1, C3b/C4b receptor, CD35, CR1, C3BR
Target/Specificity Intact human monocytes
Application Note ELISA : For coating, order Ab without BSA
Flow Cytometry : 0.5-1ug/million cells
Immunofluorescence : 1-2ug/ml
Western Blotting : 0.5-1.0 µg/ml
Immunoprecipitation : 1-2ug/500ug protein lysate
Immunohistology (Frozen & Formalin-fixed) : 0.5-1.0 µg/ml for 30 minutes at RT
(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes).
Format 0.5 ml at 200ug/ml with BSA and azide
StorageStore at 2 to 8°C.Antibody is stable for 24 months.
Precautions CD35 / CR1 (Follicular Dendritic Cell Marker) Antibody - With BSA and Azide is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CR1
Synonyms C3BR
Function Mediates cellular binding of particles and immune complexes that have activated complement.
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Present on erythrocytes, leukocytes, glomerular podocytes, and splenic follicular dendritic cells
Research Areas
Citations (0)

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Recognizes a protein of 210-220kDa, which is identified as the complement receptor 1 (CR1)/CD35. This MAb is specific for a site in CR1 that is distal from the C3b-binding site, so that it is unable to block CR1 activity. This MAb is highly specific to CR1 and shows no cross-reaction with CR2. The primary function of CR1 is to serve as the cellular receptor for C3b and C4b, the most important components of the complement system leading to clearance of foreign macromolecules. The Knops blood group system is a system of antigens located on this protein. Follicular dendritic cells (FDC) are restricted to the B-cell regions of secondary lymphoid follicles. They are CD21+/CD35+/CD1a-. This MAb labels follicular dendritic cells and follicular dendritic cell sarcoma.


1. Hogg N, et. al. European Journal of Immunology, 1984, 14:236-43.

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$ 124.00
$ 324.00
$ 454.00
Cat# AH10160
(40 western blots)
Availability: 2-3 days
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