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>   home   >   Products   >   Primary Antibodies   >    CD74 (B-Cell Marker) Antibody - With BSA and Azide   

CD74 (B-Cell Marker) Antibody - With BSA and Azide

Purified Mouse Monoclonal Antibody

  •  -  CD74 (B-Cell Marker) Antibody - With BSA and Azide AH10259
    Formalin-paraffin human tonsil stained with CD74 MAb (LN-2).
  •  -  CD74 (B-Cell Marker) Antibody - With BSA and Azide AH10259
    Formalin-paraffin human tonsil stained with CD74 Ab (LN-2). Note membrane staining.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P044233
Other Accession P04441
Reactivity Human, Mouse
Host Mouse
Clonality Monoclonal
Isotype IgG1, kappa
Clone Names LN-2
Calculated MW 33-41kDa
Additional Information
Target/Specificity SU-DHL-4 lymphoma cells
Application Note ELISA : For coating, order Ab without BSA
Flow Cytometry : 0.5-1ug/million cells
Immunofluorescence : 1-2ug/ml
Western Blotting : 0.5-1.0 µg/ml
Immunoprecipitation : 1-2ug/500ug protein lysate
Immunohistology (Frozen & Formalin-fixed) : 0.5-1.0 µg/ml for 30 minutes at RT
(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes).
Format 0.5 ml at 200ug/ml with BSA and azide
StorageStore at 2 to 8°C.Antibody is stable for 24 months.
Precautions CD74 (B-Cell Marker) Antibody - With BSA and Azide is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Citations (0)

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CD74 is a type II transmembrane protein which binds to the peptide binding groove of newly synthesized MHC class II alpha/beta heterodimers and prevents their premature association with endogenous polypeptides. CD74 is expressed primarily by antigen presenting cells, such as B-lymphocytes (from before the pre-B cell stage to before the plasma cell stage), macrophages, and monocytes, and many epithelial cells. Anti-CD74 stains predominantly germinal center lymphocytes and B-cell lymphomas, but rarely T-cell lymphomas. Anti-CD74 has been shown to be useful in differentiating atypical fibroxanthoma (-) from malignant fibrous histiocytoma (+).


1. Epstein AL et. al. J of Immunology 133: 1028-1036, 1984.
2. Marder RJ et. al. Lab Invest 52: 497-504, 1985.

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$ 124.00
$ 324.00
$ 454.00
Cat# AH10259
(40 western blots)
Availability: 2-3 days
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