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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >    Insulin-like Growth Factor-1 (IGF-1) Antibody - With BSA and Azide   

Insulin-like Growth Factor-1 (IGF-1) Antibody - With BSA and Azide

Purified Mouse Monoclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P05019
Other Accession P05017, P08025
Reactivity Human, Mouse, Rat, Rabbit
Host Mouse
Clonality Monoclonal
Isotype IgG1, kappa
Clone Names M23
Calculated MW ~7.6kDa
Additional Information
Gene ID 3479
Other Names Insulin-like growth factor I, IGF-I, Mechano growth factor, MGF, Somatomedin-C, IGF1, IBP1
Target/Specificity Purified human IGF-1 protein
Application Note ELISA : For coating, purchase antibody without BSA
Flow Cytometry : 0.5-1ug/million cells
Immunofluorescence : 1-2ug/ml
Immunoprecipitation : 1-2ug/500ug protein
Western Blotting : 0.5-1.0 µg/ml
Immunohistology (Formalin-fixed) : 1-2ug/ml for 30 min at RT
In-vitro Neutralization of Biological Activity of IGF-1 (Order Ab without Azide).
Format 0.5 ml at 200ug/ml with BSA and azide
StorageStore at 2 to 8°C.Antibody is stable for 24 months.
Precautions Insulin-like Growth Factor-1 (IGF-1) Antibody - With BSA and Azide is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name IGF1
Synonyms IBP1
Function The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in rat bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation.
Cellular Location Secreted.
Research Areas
Citations (0)

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This antibody is specific to Insulin-like Growth Factor (IGF-1) and shows minimal cross-reaction with IGF-11, Proinsulin, MSF, and Insulin. IGF-1 is a polypeptide growth factor with two isoforms that are produced by alternative splicing. Isoform 1 is also known as IGF-IB while isoform 2 is known as IGF-IA. IGF-1 stimulates the proliferation of a wide range of cell types including muscle, bone and cartilage tissue. It functions as an autocrine regulator of growth. Activation of IGF system has emerged as a key factor for tumor progression and resistance to apoptosis in many cancers like those of breast, thyroid and colon.


1. Rotwein p, et. al. (1986) J. Biol. Chem. 261: 4828-4832.
2. Sandberg-Nordqvist AC, et. al. (1993) Cancer Res. 53: 2475-2478.
3. Zheng WH, et. al. (2000) J. Neural.Transm. Suppl. 2000: 261-272.

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$ 124.00
$ 324.00
$ 454.00
Cat# AH10264
(40 western blots)
Availability: 2-3 days
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