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Napsin A Antibody

Purified Rabbit Polyclonal Antibody

  •  - Napsin A Antibody  AH10288
    Formalin-paraffin human kidney stained with Napsin-A Rabbit PAb.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O96009
Reactivity Human
Predicted Human
Host Rabbit
Clonality Polyclonal
Isotype IgG
Clone Names N/A
Calculated MW 37kDa
Additional Information
Gene ID 9476
Other Names Napsin-A, 3423-, Aspartyl protease 4, ASP4, Asp 4, Napsin-1, TA01/TA02, NAPSA, NAP1, NAPA
Target/Specificity A synthetic peptide RFDPKASSSFQANGTKFAIQYGT of human Napsin-A
Application Note Flow Cytometry : 0.5-1ug/million cells
Immunofluorescence : 1-2ug/ml
Western Blotting : 0.5-1.0 µg/ml
Immunoprecipitation : 1-2ug/500ug protein lysate
Immunohistology (formalin-fixed) : 1-2ug/ml for 30 minutes at RT
(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes).
Format 0.5 ml at 200ug/ml with BSA and azide
StorageStore at 2 to 8°C.Antibody is stable for 24 months.
PrecautionsNapsin A Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms NAP1, NAPA
Function May be involved in processing of pneumocyte surfactant precursors.
Cellular Location Secreted.
Tissue Location Expressed predominantly in adult lung (type II pneumocytes) and kidney and in fetal lung. Low levels in adult spleen and very low levels in peripheral blood leukocytes
Research Areas
Citations (0)

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Napsin is a pepsin-like aspartic proteinase connected with maturation of surfactant protein B. There are two closely related napsins, napsin A and napsin B. Napsin A is expressed as a single chain protein. Immunohistochemical studies revealed high expression levels of napsin A in human lung and kidney but low expression in spleen. Napsin A is expressed in type II pneumocytes and in adenocarcinomas of lung. The high specificity expression of napsin A in adenocarcinomas of lung is useful to distinguish primary lung adenocarcinomas from adenocarcinomas of other organs.


1. Bishop, JA et. al. Hum Pathol 41: 20-25
2. Ordonez, NG 2012 Adv Anat Pathol 19: 66-73
3. Ye, J et. al. Appl Immunhistochem Mol Morphol 19: 313-317

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$ 295.00
Cat# AH10288
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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