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CD35 / CR1 (Follicular Dendritic Cell Marker) Antibody - Without BSA and Azide

Mouse Monoclonal Antibody [Clone SPM554 ]

  • IHC -  CD35 / CR1 (Follicular Dendritic Cell Marker) Antibody - Without BSA and Azide AH10416
    Formalin-fixed, paraffin-embedded human Tonsil stained with CD35 Monoclonal Antibody (SPM554).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P17927
Other Accession 1378, 334019
Reactivity Human, Baboon, Rhesus, Cynomolgus Monkey
Host Mouse
Clonality Monoclonal
Isotype Mouse / IgG1, kappa
Clone Names SPM554
Calculated MW 210-220kDa
Additional Information
Gene ID 1378
Other Names Complement receptor type 1, C3b/C4b receptor, CD35, CR1, C3BR
Format 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
StorageStore at 2 to 8°C.Antibody is stable for 24 months.
Precautions CD35 / CR1 (Follicular Dendritic Cell Marker) Antibody - Without BSA and Azide is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CR1
Synonyms C3BR
Function Mediates cellular binding of particles and immune complexes that have activated complement.
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Present on erythrocytes, leukocytes, glomerular podocytes, and splenic follicular dendritic cells
Research Areas
Citations (0)

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Recognizes a protein of 210-220kDa, which is identified as the complement receptor 1 (CR1)/CD35. This MAb is specific for a site in CR1 that is distal from the C3b-binding site, so that it is unable to block CR1 activity. This MAb is highly specific to CR1 and shows no cross-reaction with CR2. The primary function of CR1 is to serve as the cellular receptor for C3b and C4b, the most important components of the complement system leading to clearance of foreign macromolecules. The Knops blood group system is a system of antigens located on this protein.ĀFollicular dendritic cells (FDC) are restricted to the B-cell regions of secondary lymphoid follicles. They are CD21+/CD35+/CD1a-. This MAb labels follicular dendritic cells and follicular dendritic cell sarcoma.


Hogg N, et. al. European Journal of Immunology, 1984, 14:236-43

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$ 354.00
$ 484.00
Cat# AH10416
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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