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>   home   >   Products   >   Primary Antibodies   >    TAG-72 / CA72.4 (Tumor-Associated Glycoprotein) Antibody - Without BSA and Azide   

TAG-72 / CA72.4 (Tumor-Associated Glycoprotein) Antibody - Without BSA and Azide

Mouse Monoclonal Antibody [Clone SPM536 ]

     
  • IHC -  TAG-72 / CA72.4 (Tumor-Associated Glycoprotein) Antibody - Without BSA and Azide AH10430-100
    Formalin-fixed, paraffin-embedded human Colon Carcinoma stained with TAG-72 Monoclonal Antibody (SPM536).
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, IF, FC
Other Accession 182875
Reactivity Human, Rat, Cow, Dog
Host Mouse
Clonality Monoclonal
Isotype Mouse / IgG1, kappa
Clone Names SPM536
Calculated MW 220kDa
Additional Information
Format 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
StorageStore at 2 to 8°C.Antibody is stable for 24 months.
Precautions TAG-72 / CA72.4 (Tumor-Associated Glycoprotein) Antibody - Without BSA and Azide is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Citations (0)

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Background

Recognizes an oncofetal antigen of 220kDa, identified as a tumor-associated glycoprotein (TAG-72) with properties of a mucin. This MAb defines the mucin-carried sialylated-Tn epitope. TAG-72 is usually expressed by adenocarcinomas, but is negative in mesotheliomas. Studies have reported that this antibody has 80% sensitivity and 93% specificity for pulmonary adenocarcinoma. Therefore, TAG-72 is a useful marker to distinguish between mesothelioma and adenocarcinoma. However, false positive reactions can occur so results must be interpreted with the utmost caution. This antibody may be useful in the differentiation of non-small cell carcinomas from small cell carcinomas of the lung. The combined use of anti-TAG-72 and anti-GCDFP-15 is valuable in the diagnosis of apocrine carcinoma.

References

Lottich SC et. al. Breast Cancer Research and Treatment, 1985, 6(1):49-56. | Thor A et. al. Cancer Research, 1986, 46(6):3118-24

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$ 354.00
$ 484.00
Cat# AH10430-100
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