IgG (Immunoglobulin Gamma Heavy Chain) (B-Cell Marker) Antibody - Without BSA and Azide
Mouse Monoclonal Antibody [Clone ICO-97 ]
|Application ||IF, FC|
|Other Accession||3500 (IGHG1), 3501 (IGHG2), 3502 (IGHG3), 3503 (IGHG4), 510635, P01859, P01860, P01861|
|Isotype||Mouse / IgG1, kappa|
|Other Names||Ig gamma-1 chain C region, IGHG1|
|Format||200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.|
|Storage||Store at 2 to 8°C.Antibody is stable for 24 months.|
|Precautions||IgG (Immunoglobulin Gamma Heavy Chain) (B-Cell Marker) Antibody - Without BSA and Azide is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
Recognizes a protein of 75kDa, identified as γ heavy chain of human immunoglobulins. It does not cross-react with α (IgA), μ (IgM), ε (IgE), or δ (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. This MAb is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin�s lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.
Baryshnikov AIu. Gematol Transfuziol. 1990 Aug;35(8):4-7. | Martinova T.et al., In: Problems medical biotechnology and immunological infection diseases. Vol 11, 182-186, 1996. | Baryshnikov A, and Tonevitsky A, Monoclonal antibodies in laboratory and clinic. Thesis p212, 1997
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