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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >    Cytokeratin 14 (KRT14) (Squamous Cell Marker) Antibody - Without BSA and Azide   

Cytokeratin 14 (KRT14) (Squamous Cell Marker) Antibody - Without BSA and Azide

Mouse Monoclonal Antibody [Clone LL002 ]

  • IHC -  Cytokeratin 14 (KRT14) (Squamous Cell Marker) Antibody - Without BSA and Azide AH10562
    Formalin-fixed, paraffin-embedded human Prostate stained with Cytokeratin 14 Monoclonal Antibody (LL002).
  • IHC -  Cytokeratin 14 (KRT14) (Squamous Cell Marker) Antibody - Without BSA and Azide AH10562
    Formalin-fixed, paraffin-embedded prostate stained with Cytokeratin 14 Monoclonal Antibody (LL002).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P02533
Other Accession 3861, 6545380
Reactivity Human, Mouse, Rat
Host Mouse
Clonality Monoclonal
Isotype Mouse / IgG3
Clone Names LL002
Calculated MW 50kDa
Additional Information
Gene ID 3861
Other Names Keratin, type I cytoskeletal 14, Cytokeratin-14, CK-14, Keratin-14, K14, KRT14
Format 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
StorageStore at 2 to 8°C.Antibody is stable for 24 months.
Precautions Cytokeratin 14 (KRT14) (Squamous Cell Marker) Antibody - Without BSA and Azide is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name KRT14
Function The nonhelical tail domain is involved in promoting KRT5-KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro.
Cellular Location Cytoplasm. Nucleus. Note=Expressed in both as a filamentous pattern
Tissue Location Detected in the basal layer, lowered within the more apically located layers specifically in the stratum spinosum, stratum granulosum but is not detected in stratum corneum. Strongly expressed in the outer root sheath of anagen follicles but not in the germinative matrix, inner root sheath or hair. Found in keratinocytes surrounding the club hair during telogen.
Research Areas
Citations (0)

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Cytokeratin 14 (CK14) belongs to the type I (or A or acidic) subfamily of low molecular weight keratins and exists in combination with keratin 5 (type II or B or basic). CK14 is found in basal cells of squamous epithelia, some glandular epithelia, myoepithelium, and mesothelial cells. Anti-CK14 is useful in differentiating squamous cell carcinomas from poorly differentiated epithelial tumors. Anti-CK14 is one of the specific basal markers for distinguishing between basal and non-basal subtypes of breast carcinomas. Anti-CK14 is also a good marker for differentiation of intraductal from invasive salivary duct carcinoma by the positive staining of basal cells surrounding the in-situ neoplasm as well as for differentiation of benign prostate from prostate carcinoma. Furthermore, this antibody has been useful in separating oncocytic tumors of the kidney from its renal mimics, and in identifying metaplastic carcinomas of the breast.


Leigh I M et. al. (1988) Dermatology, 91:415. | P.Purkis et al. 1990. Journal of Cell Science. 97: p39-50. | H.Schaafsma et al. 1990. American Journal Of Pathology. 136(2): p329-43. | Perkins W et. al. J Cutaneous Pathol, 1992, 19(6):476-82. | Kasper M. Histochemistry, 1991, 95(6):613-20

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$ 354.00
$ 484.00
Cat# AH10562
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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