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>   home   >   Products   >   Primary Antibodies   >    c-Myb Oncoprotein Antibody - Without BSA and Azide   

c-Myb Oncoprotein Antibody - Without BSA and Azide

Mouse Monoclonal Antibody [Clone MYB286 ]

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P01104
Other Accession 4602, 606320
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype Mouse / IgG1, kappa
Clone Names MYB286
Calculated MW ~75kDa
Additional Information
Other Names Transforming protein Myb, V-MYB
Format 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
StorageStore at 2 to 8°C.Antibody is stable for 24 months.
Precautions c-Myb Oncoprotein Antibody - Without BSA and Azide is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name V-MYB
Function DNA-binding protein that specifically recognizes the sequence 5'-YAAC[GT]G-3'. The v-Myb oncogene transforms immature myelomonocytic avian cells in culture and induces myeloblastosis (myeloid leukemia) in chickens.
Cellular Location Host nucleus.
Citations (0)

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The highly leukemogenic avian retrovirus E26 contains two oncogenes, v-Myb and v-Ets, which are expressed together as a fusion protein. The cellular homolog of v-Myb, designated c-Myb, encodes a transcription factor. Deletion or disruption of a negative regulatory domain mapping within the carboxy-terminal domain of c-Myb results in enhanced transactivating capacity and in parallel, leads to activation of its ability to transform hemopoietic cells. c-Myb is expressed preferentially, but not exclusively, in immature hemopoietic cells and its expression decreases as cells differentiate.


Gonda, T.J., et al. 1984. Expression of Myb, Myc and Fos proto-oncogenes during the differentiation of a murine myeloid leukaemia. Nature 310: 249-251

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$ 354.00
$ 484.00
Cat# AH10612
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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