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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >    TIMP-3 (Tissue Inhibitor of Metalloproteinase-3) Antibody - With BSA and Azide   

TIMP-3 (Tissue Inhibitor of Metalloproteinase-3) Antibody - With BSA and Azide

Rabbit Polyclonal Antibody

  • IHC -  TIMP-3 (Tissue Inhibitor of Metalloproteinase-3) Antibody - With BSA and Azide AH10766
    Formalin-fixed, paraffin-embedded human Placenta stained with TIMP3 Rabbit Polyclonal Antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P35625
Other Accession 7078, 644633, 714168
Reactivity Human, Mouse, Rat, Cow, Horse, Dog
Host Rabbit
Clonality Polyclonal
Isotype Rabbit / IgG
Clone Names
Calculated MW 30kDa
Additional Information
Gene ID 7078
Other Names Metalloproteinase inhibitor 3, Protein MIG-5, Tissue inhibitor of metalloproteinases 3, TIMP-3, TIMP3
Format 200ug/ml of Ab purified from rabbit anti-serum by Protein A. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA at 1.0mg/ml.
StorageStore at 2 to 8°C.Antibody is stable for 24 months.
Precautions TIMP-3 (Tissue Inhibitor of Metalloproteinase-3) Antibody - With BSA and Azide is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TIMP3
Function Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. May form part of a tissue-specific acute response to remodeling stimuli. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-9, MMP-13, MMP-14 and MMP-15.
Cellular Location Secreted, extracellular space, extracellular matrix
Research Areas
Citations (0)

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TIMP3 (tissue inhibitor of metalloproteinases 3), along with family members TIMP1, TIMP2, and TIMP4, are inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix (ECM). An imbalance between MMPs and the associated TIMPs may play a significant role in the invasive phenotype of malignant tumors. TIMP s inhibit the proteolytic invasiveness of tumor cells and normal placental trophoblast cells. TIMP-3 may be involved in regulating trophoblastic invasion of the uterus as well as in regulating remodeling of the extracellular matrix during the folding of epithelia, and in the formation, branching and expansion of epithelial tubes.


Nagase, H. et al. (2006) Cardiovasc Res 69, 562-73. | Visse, R. and Nagase, H. (2003) Circ Res 92, 827-39. |

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$ 124.00
$ 324.00
$ 454.00
Cat# AH10766
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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