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Ep-CAM / CD326 (Rat) (Epithelial Marker) Antibody - Bioreactor Concentrate

Mouse Monoclonal Antibody [Clone SPM534 ]

     
  • WB -  Ep-CAM / CD326 (Rat) (Epithelial Marker) Antibody - Bioreactor Concentrate  AH10971-01
    Western Blot of rat Colon Lysate probed with Ep-CAM Monoclonal Antibody (SPM534).
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  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF, FC
Primary Accession O55159
Other Accession 171577 (Rat)
Reactivity Rat
Host Mouse
Clonality Monoclonal
Isotype Mouse / IgG1
Clone Names SPM534
Calculated MW 40-43kDa
Additional Information
Gene ID 171577
Other Names Epithelial cell adhesion molecule, Ep-CAM, Epithelial glycoprotein 314, EGP314, Protein D5.7A, Tumor-associated calcium signal transducer 1, CD326, Epcam, Tacstd1
Format Bioreactor Concentrate with 0.05% Azide. Contact us if you require it in a different format.
StorageStore at 2 to 8°C.Antibody is stable for 24 months.
Precautions Ep-CAM / CD326 (Rat) (Epithelial Marker) Antibody - Bioreactor Concentrate is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Epcam
Synonyms Tacstd1
Function May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E (By similarity).
Cellular Location Lateral cell membrane; Single-pass type I membrane protein. Cell junction, tight junction. Note=Colocalizes with CLDN7 at the lateral cell membrane and tight junction
Citations (0)
citation

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Background

Epitope of GZ-1 and GZ-20 monoclonal antibodies are different. EGP40 is a 40-43kDa transmembrane epithelial glycoprotein, also identified as epithelial specific antigen (ESA), or epithelial cellular adhesion molecule (Ep-CAM). It is expressed on baso-lateral cell surface in most simple epithelia and a vast majority of carcinomas.

References

Litvinov SV et. al. J Cell Biol, 1994, 125:437-46. ,2. Tsubura A et. al. J Cut Pathol, 1992, 19:73-9

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$ 199.00
$ 429.00
Cat# AH10971-01
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