IL-6 (Interleukin-6) / Interferon beta-2 (Hybridoma Growth Factor) Antibody - Without BSA and Azide
Rat Monoclonal Antibody [Clone MP5-20F3 ]
|Application ||IF, FC|
|Other Accession||16193 (Mouse), 1019 (Mouse)|
|Isotype||Rat / IgG1, kappa|
|Other Names||Interleukin-6, IL-6, B-cell hybridoma growth factor, Interleukin HP-1, Il6, Il-6|
|Format||200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.|
|Storage||Store at 2 to 8°C.Antibody is stable for 24 months.|
|Precautions||IL-6 (Interleukin-6) / Interferon beta-2 (Hybridoma Growth Factor) Antibody - Without BSA and Azide is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig- secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation.|
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Provided below are standard protocols that you may find useful for product applications.
IL-6 is a potent lymphoid cell growth factor that stimulates the growth and survivability of certain B-cells and T-cells. IL-6 plays a role in host defense, acute phase reactions, immune responses, and hematopoiesis. IL-6 is expressed by T-cells, B-cells, monocytes, fibroblasts, hepatocytes, endothelial cells and keratinocytes.
Abrams J, et al. 1992. Immunol. Rev. 127:5. (ELISA Capture, Neut)Sander B, et al. 1993. J. Immunol. Meth. 166:201. (ELISA Capture, Neut)Abrams J, 1995. Curr. Prot. Immunol. John Wiley and Sons, New York. Unit 6.20. (ELISA Capture)Litton M, et al. 1994. J. Immunol Meth. 175:47. (IHC)Finkelman F, et al. 2003. Curr. Prot. Immunol. John Wiley & Sons, New York. Unit 6.28. (In Vivo Capture)Starnes HF Jr, et al. 1990. J. Immunol. 145:4185. (Neut)Riedemann NC, et al. 2003. J. Immunol. 170:503. (Neut)Rochman I, et al. 2005. J. Immunol. 174:4761. (Neut)O'Connell PJ, et al. 2006. Blood 107:1010. (ELISA Capture
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