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Ksp-Cadherin (Kidney-Specific Cadherin) / CDH16 Antibody - With BSA and Azide

Mouse Monoclonal Antibody [Clone SPM594 ]

  • IHC -  Ksp-Cadherin (Kidney-Specific Cadherin) / CDH16 Antibody - With BSA and Azide AH10986
    Formalin-fixed, paraffin-embedded human Renal Cell Carcinoma stained with KSP-Cadherin Monoclonal Antibody (SPM594)
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O75309
Other Accession 1014, 513660
Reactivity Human, Mouse, Rat, Rabbit, Dog
Host Mouse
Clonality Monoclonal
Isotype Mouse / IgG1, kappa
Clone Names SPM594
Calculated MW 130kDa
Additional Information
Gene ID 1014
Other Names Cadherin-16, Kidney-specific cadherin, Ksp-cadherin, CDH16
StorageStore at 2 to 8°C.Antibody is stable for 24 months.
Precautions Ksp-Cadherin (Kidney-Specific Cadherin) / CDH16 Antibody - With BSA and Azide is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CDH16
Function Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
Cellular Location Cell membrane; Single-pass type I membrane protein
Tissue Location Kidney specific.
Research Areas
Citations (0)

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This MAb recognizes a protein of 130kDa, identified as Ksp-cadherin. Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is suggested that Ksp-cadherin is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, Ksp-Cadherin is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels.ĀKsp-Cadherin has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma.


Shen, S.S., et al. 2005. Kidney-specific cadherin, a specific marker for the distal portion of the nephron and related renal neoplasms. Mod Pathol. 18: 933-40. | Mazal, P.R., et al. 2005. Expression of kidney-specific cadherin distinguishes chromophobe renal cell carcinoma from renal oncocytoma. Hum Pathol. 36: 22-28. |

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$ 124.00
$ 324.00
$ 454.00
Cat# AH10986
(40 western blots)
Availability: 2-3 days
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