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>   home   >   Products   >   Primary Antibodies   >   Stem Cells   >    Calponin-1 (Smooth Muscle Marker) Antibody - Without BSA and Azide   

Calponin-1 (Smooth Muscle Marker) Antibody - Without BSA and Azide

Mouse Monoclonal Antibody [Clone CALP ]

  • IHC -  Calponin-1 (Smooth Muscle Marker) Antibody - Without BSA and Azide AH11106
    Formalin-fixed, paraffin-embedded human Uterus stained with Calponin-1 Monoclonal Antibody (CALP).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P51911
Other Accession 1264, 465929
Reactivity Human, Rat
Host Mouse
Clonality Monoclonal
Isotype Mouse / IgG1, kappa
Clone Names CALP
Calculated MW 34kDa
Additional Information
Gene ID 1264
Other Names Calponin-1, Basic calponin, Calponin H1, smooth muscle, CNN1
StorageStore at 2 to 8°C.Antibody is stable for 24 months.
Precautions Calponin-1 (Smooth Muscle Marker) Antibody - Without BSA and Azide is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CNN1
Function Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity (By similarity).
Tissue Location Smooth muscle, and tissues containing significant amounts of smooth muscle
Research Areas
Citations (0)

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Multiple isoelectric variants of calponin have been identified, however only two molecular weight isoforms exist; a 34kDa form and a 29kDa form. Expression of the 29kDa form, I-calponin, is primarily restricted to muscle of the urogenital tract, whereas the higher molecular weight variant has been demonstrated in vascular and visceral smooth muscle. In Western blotting, this MAb reacts with only the 34kDa form of calponin in extracts of human aortic medial smooth muscle and is unreactive with fibroblast extracts of cultivated human foreskin. Calponin is a calmodulin, F-actin and tropomyosin binding protein, which is thought to be involved in the regulation of smooth muscle contraction. Calponin expression is restricted to smooth muscle cells and has been shown to be a marker of the differentiated (contractile) phenotype of developing smooth muscle.


Frid MG, et al. Phenotypic changes of human smooth muscle cells during development: Late expression of heavy caldesmon and calponin. Dev Biol 1992; 153:18

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$ 354.00
$ 484.00
Cat# AH11106
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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