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AFP (Alpha Fetoprotein) (Hepatocellular/Germ Cell Tumor Marker) Antibody - With BSA and Azide

Mouse Monoclonal Antibody [Clone C2 + C3 + MBS-12 ]

     
  • IHC -  AFP (Alpha Fetoprotein) (Hepatocellular/Germ Cell Tumor Marker) Antibody - With BSA and Azide AH11143-20
    Formalin-fixed, paraffin-embedded human Fetal Liver stained with AFP Monoclonal Antibody (C2 + C3 + MBS-12).
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  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC, IF, FC
Primary Accession P02771
Other Accession 174, 518808
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype Mouse / IgG's
Clone Names C2 + C3 + MBS-12
Calculated MW 70kDa
Additional Information
Gene ID 174
Other Names Alpha-fetoprotein, Alpha-1-fetoprotein, Alpha-fetoglobulin, AFP, HPAFP
StorageStore at 2 to 8°C.Antibody is stable for 24 months.
Precautions AFP (Alpha Fetoprotein) (Hepatocellular/Germ Cell Tumor Marker) Antibody - With BSA and Azide is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name AFP
Synonyms HPAFP
Function Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin. Only a small percentage (less than 2%) of the human AFP shows estrogen-binding properties.
Cellular Location Secreted.
Tissue Location Plasma. Synthesized by the fetal liver and yolk sac
Research Areas
Citations (0)
citation

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Background

It recognizes an oncofetal glycoprotein with a single chain of 70kDa, which is identified as alpha fetoprotein (AFP). This MAb is highly specific to AFP and shows no cross-reaction with other oncofetal antigens or serum albumin. AFP is normally synthesized in the liver, intestinal tract, and yolk sac of the fetus. Antibody to AFP has been shown to be useful in detecting hepatocellular carcinomas (HCC) and germ cell neoplasms, especially yolk sac tumors.

References

Lafuste, P., et al. 2002. α-fetoprotein gene expression in early and full- term human trophoblast. Placenta 23: 600-612

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$ 219.00
$ 499.00
Cat# AH11143-20
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