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>   home   >   Products   >   Primary Antibodies   >   Immunology   >    IgA Secretory Component / ECM1 Antibody   

IgA Secretory Component / ECM1 Antibody

Mouse Monoclonal Antibody [Clone SC05 ]

  • IHC -  IgA Secretory Component / ECM1 Antibody AH11168
    Formalin-fixed, paraffin-embedded human Colon Carcinoma stained with IgA Secretory Component Monoclonal Antibody (SC-05).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q16610
Other Accession 1893, 81071
Reactivity Human, Rat
Host Mouse
Clonality Monoclonal
Isotype Mouse / IgG1, kappa
Clone Names SC05
Calculated MW ~80kDa
Additional Information
Gene ID 1893
Other Names Extracellular matrix protein 1, Secretory component p85, ECM1
StorageStore at 2 to 8°C.Antibody is stable for 24 months.
Precautions IgA Secretory Component / ECM1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ECM1
Function Involved in endochondral bone formation as negative regulator of bone mineralization. Stimulates the proliferation of endothelial cells and promotes angiogenesis. Inhibits MMP9 proteolytic activity.
Cellular Location Secreted, extracellular space, extracellular matrix
Tissue Location Expressed in breast cancer tissues. Little or no expression observed in normal breast tissues. Expressed in skin; wide expression is observed throughout the dermis with minimal expression in the epidermis.
Research Areas
Citations (0)

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This MAb reacts with a reduction-resistant epitope present in both free and SIgA bound Secretory Component. It does not react with the cell lines lacking secretory component. The antibody is useful for studying the distribution and level of both free and bound secretory component. Secretory component is differentially expressed in epithelium, and the antibody is a popular marker for identifying subpopulations of epithelial cells and epithelial differentiation. The Secretory component antibody is a useful research tool for studying mucosal immunity, inflammation, remodeling, differentiation and tumorigenesis, all processes associated with differential secretory component expression.


Bartek J et. al. Histochemistry 91:235-244 (1989). | Int. J. Cancer, 42, 638-641 (1988). | Histochem J., 22, (1990)

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$ 324.00
Cat# AH11168
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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