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Fibronectin (8th Type III Repeat) Antibody

Mouse Monoclonal Antibody [Clone 568]

  • IHC -  Fibronectin (8th Type III Repeat) Antibody AH11225
    Formalin-fixed, paraffin-embedded human Renal Cell Carcinoma stained with Fibronectin Monoclonal Antibody (568).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P02751
Other Accession 2335, 203717
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype Mouse / IgG1, kappa
Clone Names 568
Calculated MW 220kDa (monomer); 440kDa (dimer)
Additional Information
Gene ID 2335
Other Names Fibronectin, FN, Cold-insoluble globulin, CIG, Anastellin, Ugl-Y1, Ugl-Y2, Ugl-Y3, FN1, FN
StorageStore at 2 to 8°C.Antibody is stable for 24 months.
Precautions Fibronectin (8th Type III Repeat) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name FN1
Synonyms FN
Function Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts.
Cellular Location Secreted, extracellular space, extracellular matrix
Tissue Location Plasma FN (soluble dimeric form) is secreted by hepatocytes. Cellular FN (dimeric or cross-linked multimeric forms), made by fibroblasts, epithelial and other cell types, is deposited as fibrils in the extracellular matrix. Ugl-Y1, Ugl-Y2 and Ugl-Y3 are found in urine.
Research Areas
Citations (0)

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Epitope of this MAb is located in the 8th type III repeat in the cell-binding region of fibronectin. Fibronectins are disulfide-linked, dimeric glycoproteins of ~440kDa. They possess at least four binding sites for collagen, glycosaminoglycans, transglutaminase, and a cell surface receptor. Fibronectins are involved in cell adhesion, tissue organization, and wound healing. Fibronectins are present in basement membranes, interstitial connective tissue matrix, and blood. Cellular fibronectin is widely distributed in the stroma of many malignant tumors. This MAb is excellent for staining of formalin-fixed, paraffin-embedded tissues.


Christensen, L., et al., APMIS, 98(7), 615-623 (1990). | Christensen, L., et al., APMIS, suppl. 26, 1-39 (1992). | Ljubimov AV et. al. Lab Investigation, 1995; 72:461-473

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$ 324.00
Cat# AH11225
(40 western blots)
Availability: 2-3 days
Bulk Size
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