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FSH-beta (Follicle Stimulating Hormone-beta) Antibody - With BSA and Azide

Mouse Monoclonal Antibody [Clone FSHb/1062 ]

     
  • IHC -  FSH-beta (Follicle Stimulating Hormone-beta) Antibody - With BSA and Azide AH11245-20
    Formalin-fixed, paraffin-embedded human Pituitary stained with FSH-beta Monoclonal Antibody (FSHb/1062).
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC, IF, FC
Primary Accession P01225
Other Accession 2488, 36975
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype Mouse / IgG1, kappa
Clone Names FSHb/1062
Calculated MW 22kDa
Additional Information
Gene ID 2488
Other Names Follitropin subunit beta, Follicle-stimulating hormone beta subunit, FSH-B, FSH-beta, Follitropin beta chain, FSHB
StorageStore at 2 to 8°C.Antibody is stable for 24 months.
Precautions FSH-beta (Follicle Stimulating Hormone-beta) Antibody - With BSA and Azide is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name FSHB
Function Stimulates development of follicle and spermatogenesis in the reproductive organs.
Cellular Location Secreted.
Research Areas
Citations (0)

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Background

This MAb reacts with a protein of 22kDa, identified as beta sub-unit of FSH. It does not cross react with the alpha sub-unit. Follicle stimulating hormone (FSH) is a hormone synthesized and secreted by gonadotrophs in the anterior pituitary gland. In the ovary, FSH stimulates the growth of immature Graafian follicles to maturation. As the follicle grows, it releases inhibin, which deactivates the FSH production. In men, FSH enhances the production of androgen-binding protein by the Sertoli cells of the testis and is critical for spermatogenesis. FSH and LH act synergistically in reproduction. FSH is a useful marker in the classification of pituitary tumors and the study of pituitary disease.

References

Schmidt M et al. Pathol Res Pract. 2001;197(10):663-9 | La Rosa S et al. Virchows Arch. 2000 Sep;437(3):264-9 | Zheng W et al. Gynecol Oncol. 2000 jan;76(1):80-

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$ 124.00
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Cat# AH11245-20
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