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>   home   >   Products   >   Primary Antibodies   >   Stem Cells   >    CD15 / FUT4 (Reed-Sternberg Cell Marker) Antibody - Without BSA and Azide   

CD15 / FUT4 (Reed-Sternberg Cell Marker) Antibody - Without BSA and Azide

Mouse Monoclonal Antibody [Clone FR4A5 ]

     
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IF, FC
Primary Accession P22083
Other Accession 2526, 654379
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype Mouse / IgM, kappa
Clone Names FR4A5
Calculated MW ~220kDa (Glycoprotein)
Additional Information
Gene ID 2526
Other Names Alpha-(1, 3)-fucosyltransferase 4, 2.4.1.-, ELAM-1 ligand fucosyltransferase, Fucosyltransferase 4, Fucosyltransferase IV, Fuc-TIV, FucT-IV, Galactoside 3-L-fucosyltransferase, FUT4, ELFT, FCT3A
StorageStore at 2 to 8°C.Antibody is stable for 24 months.
Precautions CD15 / FUT4 (Reed-Sternberg Cell Marker) Antibody - Without BSA and Azide is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name FUT4
Synonyms ELFT, FCT3A
Function May catalyze alpha-1,3 glycosidic linkages involved in the expression of Lewis X/SSEA-1 and VIM-2 antigens.
Cellular Location Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Note=Membrane-bound form in trans cisternae of Golgi
Research Areas
Citations (0)

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Background

CD15 plays a role in mediating phagocytosis, bactericidal activity, and chemotaxis. It is present on >95% of granulocytes including neutrophils and eosinophils and to a lesser degree on monocytes. In addition, CD15 is expressed in Reed-Sternberg cells and some epithelial cells. CD15 antibody is very useful in the identification of Hodgkin’s disease. CD15 is occasionally expressed in large cell lymphomas of both B and T phenotypes which otherwise have a quite distinct histological appearance.

References

Bettelheim, P., et al., Cluster Report: CD15, in : Knapp, W., et al. (eds), Leucocyte Typing IV, Oxford Univ. Press, pp 798-799. | Hogg, N., et al., Myeloid antigens: new and previously defines clusters, in: McMichae, A.J., et al (eds), Leucocyte Typing III, Oxford Univ. Press, pp 576-602

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$ 354.00
$ 484.00
Cat# AH11273
Size:
Quantity:
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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