|Application ||WB, IHC, IF, FC|
|Other Accession||2670, 514227|
|Reactivity||Human, Mouse, Rat, Rabbit, Pig, Chicken, Cow|
|Isotype||Mouse / IgG1|
|Other Names||Glial fibrillary acidic protein, GFAP, GFAP|
|Storage||Store at 2 to 8°C.Antibody is stable for 24 months.|
|Precautions||GFAP (Astrocyte & Neural Stem Cell Marker) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||GFAP, a class-III intermediate filament, is a cell- specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells.|
|Cellular Location||Cytoplasm. Note=Associated with intermediate filaments|
|Tissue Location||Expressed in cells lacking fibronectin.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
This MAb recognizes a protein of ~50kDa which is identified as Glial Fibrillary Acidic Protein (GFAP). It shows no cross-reaction with other intermediate filament proteins. GFAP is specifically found in astroglia. GFAP is a very popular marker for localizing benign astrocyte and neoplastic cells of glial origin in the central nervous system. Antibody to GFAP is useful in differentiating primary gliomas from metastatic lesions in the brain and for documenting astrocytic differentiation in tumors outside the CNS.
Herpers MJ et. Al. 1986, Acta Neuropathol, 70:333-339. | Van Muijen GN et. al. 1987, Lab Invest, 57:359-369. | Debus E, et. al. 1983, Differentiation, 25(2):193-203. |
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.