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>   home   >   Products   >   Primary Antibodies   >   Immunology   >    CD57 / B3GAT1 (Natural Killer Cell Marker) Antibody   

CD57 / B3GAT1 (Natural Killer Cell Marker) Antibody

Mouse Monoclonal Antibody [Clone HNK-1 + NK-1 ]

  • IHC -  CD57 / B3GAT1 (Natural Killer Cell Marker) Antibody AH11307
    Formalin-fixed, paraffin-embedded human Tonsil stained with CD57 Monoclonal Antibody (HNK-1 + NK-1).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9P2W7
Other Accession 27087, 381050
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype Mouse / IgM's
Clone Names HNK-1 + NK-1
Calculated MW ~110kDa
Additional Information
Gene ID 27087
Other Names Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1,, Beta-1, 3-glucuronyltransferase 1, Glucuronosyltransferase P, GlcAT-P, UDP-GlcUA:glycoprotein beta-1, 3-glucuronyltransferase, GlcUAT-P, B3GAT1, GLCATP
StorageStore at 2 to 8°C.Antibody is stable for 24 months.
Precautions CD57 / B3GAT1 (Natural Killer Cell Marker) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name B3GAT1
Synonyms GLCATP
Function Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on glycoproteins. Can also play a role in glycosaminoglycan biosynthesis. Substrates include asialo- orosomucoid (ASOR), asialo-fetuin, and asialo-neural cell adhesion molecule. Requires sphingomyelin for activity: stearoyl- sphingomyelin was the most effective, followed by palmitoyl- sphingomyelin and lignoceroyl-sphingomyelin. Activity was demonstrated only for sphingomyelin with a saturated fatty acid and not for that with an unsaturated fatty acid, regardless of the length of the acyl group (By similarity).
Cellular Location Golgi apparatus membrane; Single-pass type II membrane protein
Tissue Location Mainly expressed in the brain.
Research Areas
Citations (0)

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Anti-CD57 marks a subset of lymphocytes known as natural killer (NK) cells. Follicular center cell lymphomas often contain many NK cells within the neoplastic follicles. Anti-CD57 also stains neuroendocrine cells and their derived tumors, including carcinoid tumor and medulloblastoma. Anti-CD57 can also be useful in separating type B3 thymoma from thymic carcinoma when combined with a panel that includes antibodies against GLUT1, CD5, and CEA.


Abo T et. al. J Immunol, 1982, 129(4):1758-61. | Abo T et al. J Immunology, 1982, 129:1752-7

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$ 324.00
Cat# AH11307
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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