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>   home   >   Products   >   Primary Antibodies   >   Cardiovascular   >    Blood Group Antigen H Type 2 (CD173) Antibody - Without BSA and Azide   

Blood Group Antigen H Type 2 (CD173) Antibody - Without BSA and Azide

Mouse Monoclonal Antibody [Clone 19-OLE ]

     
  • IHC -  Blood Group Antigen H Type 2 (CD173) Antibody - Without BSA and Azide AH11346-100
    Formalin-fixed, paraffin-embedded human Colon Carcinoma stained with Blood Group Antigen H Type 2 Monoclonal Antibody (19-OLE)
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC, IF
Primary Accession P16442
Other Accession 28, 654423
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype Mouse / IgM, kappa
Clone Names 19-OLE
Calculated MW Multiple KDa
Additional Information
Gene ID 28
Other Names Histo-blood group ABO system transferase, Fucosylglycoprotein 3-alpha-galactosyltransferase, Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase, Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase, 2.4.1.40, Glycoprotein-fucosylgalactoside alpha-galactosyltransferase, 2.4.1.37, Histo-blood group A transferase, A transferase, Histo-blood group B transferase, B transferase, NAGAT, Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase soluble form, ABO
StorageStore at 2 to 8°C.Antibody is stable for 24 months.
Precautions Blood Group Antigen H Type 2 (CD173) Antibody - Without BSA and Azide is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ABO
Function This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity.
Cellular Location Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Secreted. Note=Membrane- bound form in trans cisternae of Golgi. Secreted into the body fluid
Research Areas
Citations (0)

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Background

Recognizes the blood group H type 2 antigens, trisaccharide FucĪ �1-2GalĪ �1-4GlcNAcĪ �1 of human origin. This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity. It is expressed on endothelial cells, epithelial cells and granulocytes. Increased expression of this antigen has been observed on some tumor tissues such as gastric carcinomas, urothelial carcinomas, and colon carcinomas.

References

Bara J, Daher N, Mollicone R, Oriol R. Immunohistological patterns of 20 monoclonal antibodies against non-A, non-B glycoconjugates in normal human pyloric and duodenal mucosae. Blood TransfImmunohae- matol. 1987; 30:685-692. | Blood transfusion and immunohaematology, Ph Rouger, D Anstee and Ch Salmon (Eds), Arnette, France 30 (5), p. 353-720, 1987. | Norwalk Virus Binds to Histo-Blood Group Antigens Present on Gastroduodenal Epithelial Cells of Secretor Individuals. SEVERINE MARIONNEAU, NATHALIE RUVOE �N, BEATRICE LE MOULLAC–VAIDYE, MONIQUE CLEMENT, ANNE CAILLEAU–THOMAS, GUILLERMO RUIZ–PALACOIS, PENGWEI HUANG, XI JIANG, and JACQUES LE PENDU. GASTROENTEROLOGY 2002;122:1967–1977. | Expression of Mucin Peptide and Blood Group ABH- and Lewis-Related Carbohydrate Antigens in Normal Human Conjunctiva. Catherine Garcher, Jacques Bara, Alain Bron, and Rafael Oriol. Invest Ophthalmol Vis Sci. 1994;35:1184-1191

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Cat# AH11346-100
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