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>   home   >   Products   >   Primary Antibodies   >   Cardiovascular   >    Blood Group Antigen A (CD173) Antibody - With BSA and Azide   

Blood Group Antigen A (CD173) Antibody - With BSA and Azide

Mouse Monoclonal Antibody [Clone 3-3A ]

  • IHC -  Blood Group Antigen A (CD173) Antibody - With BSA and Azide AH11362
    Formalin-fixed, paraffin-embedded human Colon Carcinoma stained with Blood Group Antigen A Monoclonal Antibody (3-3A)
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P16442
Other Accession 28, 654423
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype Mouse / IgG1, kappa
Clone Names 3-3A
Calculated MW Multiple KDa
Additional Information
Gene ID 28
Other Names Histo-blood group ABO system transferase, Fucosylglycoprotein 3-alpha-galactosyltransferase, Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase, Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase,, Glycoprotein-fucosylgalactoside alpha-galactosyltransferase,, Histo-blood group A transferase, A transferase, Histo-blood group B transferase, B transferase, NAGAT, Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase soluble form, ABO
StorageStore at 2 to 8°C.Antibody is stable for 24 months.
Precautions Blood Group Antigen A (CD173) Antibody - With BSA and Azide is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ABO
Function This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity.
Cellular Location Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Secreted. Note=Membrane- bound form in trans cisternae of Golgi. Secreted into the body fluid
Research Areas
Citations (0)

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This MAb preferably reacts with determinants of chain A and H type 3Ā(Gal1-3GalNAc-R) and 4 (Gal1-3GalNAc-R), but not with type 1 and 2 chain structures. It is not reactive with immuno-dominant A trisaccharide. This MAb is applicable for tissue staining in tumor patients with blood groups A and AB. It shows a highly heterogeneous reactivity in human colon tumor tissue and adjacent mucosa. Blood-group antigens are generally defined as molecules formed by sequential addition of saccharides to the carbohydrate side chains of lipids and proteins detected on erythrocytes and certain epithelial cells. The A, B and H antigens are reported to undergo modulation during malignant cellular transformation. Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids and glycoproteins. They are usually mucin-type, and are detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter-related specificities belong to this group of antigens, including A, B, H, Lewis A, Lewis B, Lewis X, Lewis Y, and precursor type 1 chain antigens.


Blood transfusion and immunohaematology, Ph Rouger, D Anstee and Ch Salmon (Eds) -Arnette, France 30 (5) 353-720, (1987). | Biochem. J. 254, 185-193 (1988)

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$ 124.00
$ 324.00
$ 454.00
Cat# AH11362
(40 western blots)
Availability: 2-3 days
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