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HLA-ABC (MHC I) Antibody - Without BSA and Azide

Mouse Monoclonal Antibody [Clone 246-B8.E7 ]

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P01889
Other Accession 3105, 181244, 654404, 77961, P30443, P30499
Reactivity Human, Mouse
Host Mouse
Clonality Monoclonal
Isotype Mouse / IgG2a, kappa
Clone Names 246-B8.E7
Calculated MW ~41kDa
Additional Information
Gene ID 3106
Other Names HLA class I histocompatibility antigen, B-7 alpha chain, MHC class I antigen B*7, HLA-B, HLAB
StorageStore at 2 to 8°C.Antibody is stable for 24 months.
Precautions HLA-ABC (MHC I) Antibody - Without BSA and Azide is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name HLA-B
Synonyms HLAB
Function Involved in the presentation of foreign antigens to the immune system.
Cellular Location Membrane; Single-pass type I membrane protein
Research Areas
Citations (0)

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Reacts with a monomorphic determinant of human major histocompatibility (MHC) class I antigens (HLA-A, B and C). Human MHC class I antigens are expressed constitutively on all nucleated cells lymphocytes such as lymphocytes, thymocytes, granulocytes, and bone marrow cells and are absent on erythrocytes. MHC class I antigens play a role in class I MHC-associated antigen presentation, inhibition of NK cell cytotoxicity, tumor surveillance, and tissue allotransplantation.


Young NT et al. Killer cell inhibitory receptor interactions with HLA class I molecules: implications for alloreactivity and transplantation. Hum Immunol 1997, 52(1):1-11 | Krensky AM et al Immunomodulation by HLA class I-derived peptides. Transplant Proc 1996, 28(6):3026-8 | Hansen JA et al The HLA system in clinical marrow transplantation. Hematol Oncol Clin North Am 1990, 4(3):507-515

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$ 354.00
$ 484.00
Cat# AH11399
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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