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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >    CD50 / ICAM-3 Antibody   

CD50 / ICAM-3 Antibody

Mouse Monoclonal Antibody [Clone SPM505 ]

  • IHC -  CD50 / ICAM-3 Antibody AH11488
    Formalin-fixed, paraffin-embedded human Tonsil stained with CD50 Monoclonal Antibody (SPM505)
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P32942
Other Accession 3385, 354563
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype Mouse / IgG2b, kappa
Clone Names SPM505
Calculated MW 110-160kDa
Additional Information
Gene ID 3385
Other Names Intercellular adhesion molecule 3, ICAM-3, CDw50, ICAM-R, CD50, ICAM3
StorageStore at 2 to 8°C.Antibody is stable for 24 months.
Precautions CD50 / ICAM-3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ICAM3
Function ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM3 is also a ligand for integrin alpha-D/beta-2.
Cellular Location Membrane; Single-pass type I membrane protein
Research Areas
Citations (0)

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Recognizes the D1 domain of an N-glycosylated glycoprotein of 120kDa with intra-chain disulfide bonds, identified as CD50 or ICAM-3. CD50 is the major ligand for LFA-1 (CD11a/CD18) and may have signaling role to increase adhesion. It is expressed on thymocytes and T lymphocytes and is resistant to treatment with phosphatidylinositol (PI) phospholipase C. This MAb is excellent for staining of formalin/paraffin tissues.


LeukocyteTyping V (S.F. Schlossman, et al, eds.) Oxford University Press, Oxford (1995)p. 1546-1547, 1578-1579. | C.L. Holness, et al, (1995) J Biol Chem 270: 877-884. | Y. van Kooyk,et al, (1996) J Exp Med 183:1247-1252. | Leukocyte TypingVI (T. Kishimoto, et al, eds.) GarlandPublishing, Inc., New York (1997) p.403-409

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$ 324.00
Cat# AH11488
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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