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Interferon gamma (IFNG) Antibody - With BSA and Azide

Mouse Monoclonal Antibody [Clone SPM408 ]

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P01579
Other Accession 3458, 856
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype Mouse / IgG1, kappa
Clone Names SPM408
Calculated MW 20-25kDa
Additional Information
Gene ID 3458
Other Names Interferon gamma, IFN-gamma, Immune interferon, IFNG
StorageStore at 2 to 8°C.Antibody is stable for 24 months.
Precautions Interferon gamma (IFNG) Antibody - With BSA and Azide is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.
Cellular Location Secreted.
Tissue Location Released primarily from activated T lymphocytes
Research Areas
Citations (0)

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Recognizes a protein of 20-25kDa, identified as human interferon. This MAb is specific to human IFN- and recognizes both recombinant and native human IFN-γ. It does not neutralize the activity of IFN-. T lymphocytes and NK cells mainly produce IFN-. It is a pleiotropic cytokine involved in the regulation of nearly all phases of immune and inflammatory responses, including the activation, growth and differentiation of T cell, B cells, macrophages, NK cells and other cell types such as endothelial cells and fibroblasts. It has weak anti-viral and anti-proliferative activity, and potentiates the antiviral and anti-tumor effects of IFN- (type I interferon).


Vilcek J. Forty years of interferon, forty years of cytokines. Cytokine Growth Factor Rev 1997,8(4):239 | Farrar MA and Schreiber RD. The molecular cell biology of interferon-gamma and its receptor. Annu Rev Immunol 1993, 11:571-611 | Vilcek J et al. Induction of human interferon gamma with phorbol esters and phytohemagglutinin. Methods Enzymol 1986,119:48-54 |

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$ 124.00
$ 324.00
$ 454.00
Cat# AH11505
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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