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Mouse Monoclonal Antibody [Clone IG217 ]
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, IF, FC |
|---|---|
| Primary Accession | P01857 |
| Other Accession | 3500 (IGHG1), 3501 (IGHG2), 3502 (IGHG3), 3503 (IGHG4), 510635, P01859, P01860, P01861 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | Mouse / IgG1, kappa |
| Clone Names | IG217 |
| Calculated MW | 75kDa |
| Other Names | Ig gamma-1 chain C region, IGHG1 |
|---|---|
| Storage | Store at 2 to 8°C.Antibody is stable for 24 months. |
| Precautions | IgG (Immunoglobulin Gamma Heavy Chain) (B-Cell Marker) Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | IGHG1 |
|---|---|
| Cellular Location | Secreted. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Recognizes a protein of 75kDa, identified as γ heavy chain of human immunoglobulins. It reacts with all sub-classes of γ chain of human immunoglobulins. It does not cross-react with α (IgA), μ (IgM), ε (IgE), or δ (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. This MAb is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin�s lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.
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