IgG (Immunoglobulin Gamma Heavy Chain) (B-Cell Marker) Antibody - Without BSA and Azide
Mouse Monoclonal Antibody [Clone B33/20 ]
|Application ||IHC-P, IF, FC|
|Other Accession||3500 (IGHG1), 3501 (IGHG2), 3502 (IGHG3), 3503 (IGHG4), 510635, P01859, P01860, P01861|
|Isotype||Mouse / IgG1, kappa|
|Other Names||Ig gamma-1 chain C region, IGHG1|
|Storage||Store at 2 to 8°C.Antibody is stable for 24 months.|
|Precautions||IgG (Immunoglobulin Gamma Heavy Chain) (B-Cell Marker) Antibody - Without BSA and Azide is for research use only and not for use in diagnostic or therapeutic procedures.|
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Recognizes a protein of 75kDa, identified as γ heavy chain of human immunoglobulins. Its epitope maps in CH2 domain of Fc region of IgG. It reacts with all sub-classes of γ chain of human immunoglobulins. It does not cross-react with α (IgA), μ (IgM), ε (IgE), or δ (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. This MAb is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin�s lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.
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