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Androgen Receptor (Marker of Androgen Dependence) Antibody - Without BSA and Azide

Mouse Monoclonal Antibody [Clone AR441 + DHTR/882 ]

  • IHC -  Androgen Receptor (Marker of Androgen Dependence) Antibody - Without BSA and Azide AH11602
    Formalin-fixed, paraffin-embedded human Prostate Carcinoma stained with Androgen Receptor Monoclonal Antibody (AR441 + DHTR/882).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P10275
Other Accession 367, 496240
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype Mouse / IgG's
Clone Names AR441 + DHTR/882
Calculated MW 110kDa
Additional Information
Gene ID 367
Other Names Androgen receptor, Dihydrotestosterone receptor, Nuclear receptor subfamily 3 group C member 4, AR, DHTR, NR3C4
StorageStore at 2 to 8°C.Antibody is stable for 24 months.
Precautions Androgen Receptor (Marker of Androgen Dependence) Antibody - Without BSA and Azide is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name AR
Synonyms DHTR, NR3C4
Function Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins. Transcription activation is down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3.
Cellular Location Nucleus. Cytoplasm. Note=Predominantly cytoplasmic in unligated form but translocates to the nucleus upon ligand-binding. Can also translocate to the nucleus in unligated form in the presence of GNB2L1
Tissue Location Isoform 2 is mainly expressed in heart and skeletal muscle.
Research Areas
Citations (0)

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Recognizes a protein of 110kDa, which is identified as androgen receptor (AR). It reacts with full length, and the newly described A form of the receptor. It does not cross react with estrogen, progesterone, or glucocorticoid receptors. The expression of AR is reportedly inversely correlated with histologic grade i.e. well differentiated prostate tumors show higher expression than the poorly differentiated tumors. In prostate cancer, AR has been proposed, as a marker of hormone-responsiveness and thus it may be useful in identifying patients likely to benefit from anti-androgen therapy. Anti-androgen receptor has been useful clinically in differentiating morpheaform basal cell carcinoma (mBCC) from desmoplastic trichoepithelioma (DTE) in the skin.ĀThis MAb is superb for staining of formalin/paraffin tissues.


J�nne OA, et al. Androgen receptor and mechanism of androgen action. Ann Med 1993; 25:8

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$ 354.00
$ 484.00
Cat# AH11602
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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